Difference between revisions of "YNL186W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005130 YNL186W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''UBP10 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''UBP10 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XIV:289500..291878 | |nowrap| Chr XIV:289500..291878 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005130 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YNL186W:''' Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus<ref name='S000074445'>Kahana A (2001) The deubiquitinating enzyme Dot4p is involved in regulating nutrient uptake. Biochem Biophys Res Commun 282(4):916-20 {{SGDpaper|S000074445}} PMID 11352638</ref><ref name='S000047238'>Singer MS, et al. (1998) Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150(2):613-32 {{SGDpaper|S000047238}} PMID 9755194</ref><ref name='S000042118'>Kahana A and Gottschling DE (1999) DOT4 links silencing and cell growth in Saccharomyces cerevisiae. Mol Cell Biol 19(10):6608-20 |
{{SGDpaper|S000042118}} PMID 10490600</ref> | {{SGDpaper|S000042118}} PMID 10490600</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Revision as of 07:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YNL186W |
| Gene name | UBP10 |
| Aliases | DOT4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:289500..291878 |
| Primary SGDID | S000005130 |
Description of YNL186W: Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus[1][2][3]
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Community Commentary
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Interactions
Two Hybrid
Two Hybrid interaction with SIR4
The N-terminal 250 aa of Ubp10p interacts with the C-terminus of Sir4p (residues 839-1358). [3] [4]
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References
See Help:References on how to add references
- ↑ Kahana A (2001) The deubiquitinating enzyme Dot4p is involved in regulating nutrient uptake. Biochem Biophys Res Commun 282(4):916-20 SGD PMID 11352638
- ↑ Singer MS, et al. (1998) Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150(2):613-32 SGD PMID 9755194
- ↑ 3.0 3.1 Kahana A and Gottschling DE (1999) DOT4 links silencing and cell growth in Saccharomyces cerevisiae. Mol Cell Biol 19(10):6608-20
SGD PMID 10490600 Cite error: Invalid
<ref>tag; name "S000042118" defined multiple times with different content - ↑ submitted by Daniel E. Gottschling on 2003-03-17
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
