Difference between revisions of "YLR133W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004123 YLR133W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CKI1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CKI1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XII:408446..410194 | |nowrap| Chr XII:408446..410194 | ||
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+ | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004123 | ||
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<br> | <br> | ||
− | '''Description of | + | '''Description of YLR133W:''' Choline kinase, catalyzes the first step in the CDP-choline pathway phosphatidylcholine synthesis (Kennedy pathway); mRNA expression is regulated by inositol and choline, enzyme activity is stimulated by phosphorylation by protein kinase<ref name='S000062282'>Kim KH, et al. (1998) Expression, purification, and characterization of choline kinase, product of the CKI gene from Saccharomyces cerevisiae. J Biol Chem 273(12):6844-52 {{SGDpaper|S000062282}} PMID 9506987</ref><ref name='S000059477'>Dowd SR, et al. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. The role of the CDP-choline pathway. J Biol Chem 276(6):3756-63 {{SGDpaper|S000059477}} PMID 11078727</ref><ref name='S000056873'>Hosaka K, et al. (1989) Cloning and characterization of the yeast CKI gene encoding choline kinase and its expression in Escherichia coli. J Biol Chem 264(4):2053-9 {{SGDpaper|S000056873}} PMID 2536698</ref><ref name='S000056764'>Hosaka K, et al. (1990) Repression of choline kinase by inositol and choline in Saccharomyces cerevisiae. J Bacteriol 172(4):2005-12 |
{{SGDpaper|S000056764}} PMID 2156807</ref> | {{SGDpaper|S000056764}} PMID 2156807</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
Systematic name | YLR133W |
Gene name | CKI1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XII:408446..410194 |
Primary SGDID | S000004123 |
Description of YLR133W: Choline kinase, catalyzes the first step in the CDP-choline pathway phosphatidylcholine synthesis (Kennedy pathway); mRNA expression is regulated by inositol and choline, enzyme activity is stimulated by phosphorylation by protein kinase[1][2][3][4]
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References
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- Jump up ↑ Kim KH, et al. (1998) Expression, purification, and characterization of choline kinase, product of the CKI gene from Saccharomyces cerevisiae. J Biol Chem 273(12):6844-52 SGD PMID 9506987
- Jump up ↑ Dowd SR, et al. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. The role of the CDP-choline pathway. J Biol Chem 276(6):3756-63 SGD PMID 11078727
- Jump up ↑ Hosaka K, et al. (1989) Cloning and characterization of the yeast CKI gene encoding choline kinase and its expression in Escherichia coli. J Biol Chem 264(4):2053-9 SGD PMID 2536698
- Jump up ↑ Hosaka K, et al. (1990) Repression of choline kinase by inositol and choline in Saccharomyces cerevisiae. J Bacteriol 172(4):2005-12 SGD PMID 2156807
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