Difference between revisions of "YDL216C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002375 YDL216C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RRI1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RRI1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr IV:70320..68998 | |nowrap| Chr IV:70320..68998 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002375 | ||
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| − | '''Description of | + | '''Description of YDL216C:''' Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling<ref name='S000071980'>Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 {{SGDpaper|S000071980}} PMID 12446563</ref><ref name='S000071602'>Wee S, et al. (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3():15 {{SGDpaper|S000071602}} PMID 12186635</ref><ref name='S000071600'>Cope GA, et al. (2002) Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298(5593):608-11 |
{{SGDpaper|S000071600}} PMID 12183637</ref> | {{SGDpaper|S000071600}} PMID 12183637</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
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| Systematic name | YDL216C |
| Gene name | RRI1 |
| Aliases | CSN5, JAB1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:70320..68998 |
| Primary SGDID | S000002375 |
Description of YDL216C: Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling[1][2][3]
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References
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- ↑ Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 SGD PMID 12446563
- ↑ Wee S, et al. (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3():15 SGD PMID 12186635
- ↑ Cope GA, et al. (2002) Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298(5593):608-11 SGD PMID 12183637
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