Difference between revisions of "YOR266W"
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 12:02, 21 February 2007
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Systematic name | YOR266W |
Gene name | PNT1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XV:821022..822293 |
Description of YOR266W: Mitochondrial inner membrane protein involved in export of proteins from the mitochondrial matrix; overexpression of PNT1 confers resistance to the anti-Pneumocystis carinii drug pentamidine, and deletion confers increased sensitivity[1][2]
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References
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- ↑ He S and Fox TD (1999) Mutations affecting a yeast mitochondrial inner membrane protein, pnt1p, block export of a mitochondrially synthesized fusion protein from the matrix. Mol Cell Biol 19(10):6598-607 SGD PMID 10490599
- ↑ Ludewig G and Staben C (1994) Characterization of the PNT1 pentamidine resistance gene of Saccharomyces cerevisiae. Antimicrob Agents Chemother 38(12):2850-6 SGD PMID 7695273
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