Difference between revisions of "YOR130C"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YOR130C
Gene name ORT1
Aliases ARG11
Feature type ORF, Verified
Coordinates Chr XV:570808..569930


Description of YOR130C: Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome[1][2]




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References

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  1. Palmieri L, et al. (1997) Identification of the yeast ARG-11 gene as a mitochondrial ornithine carrier involved in arginine biosynthesis. FEBS Lett 410(2-3):447-51 SGD PMID 9237680
  2. Crabeel M, et al. (1996) The ARG11 gene of Saccharomyces cerevisiae encodes a mitochondrial integral membrane protein required for arginine biosynthesis. J Biol Chem 271(40):25011-8 SGD PMID 8798783

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