Difference between revisions of "YOL027C"
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| − | '''Description of {{PAGENAME}}:''' Mitochondrial inner membrane protein, required for K+/H+ exchange | + | '''Description of {{PAGENAME}}:''' Mitochondrial inner membrane protein, involved in membrane integration of a subset of mitochondrial proteins; required for K+/H+ exchange; associates with mitochondrial ribosomes; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome<ref name='S000114395'>Frazier AE, et al. (2006) Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery. J Cell Biol 172(4):553-64 {{SGDpaper|S000114395}} PMID 16476776</ref><ref name='S000082022'>Froschauer E, et al. (2005) Electroneutral K+/H+ exchange in mitochondrial membrane vesicles involves Yol027/Letm1 proteins. Biochim Biophys Acta 1711(1):41-8 {{SGDpaper|S000082022}} PMID 15904662</ref><ref name='S000076911'>Nowikovsky K, et al. (2004) The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome. J Biol Chem 279(29):30307-15 {{SGDpaper|S000076911}} PMID 15138253</ref><ref name='S000071517'>Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 |
{{SGDpaper|S000071517}} PMID 11907266</ref> | {{SGDpaper|S000071517}} PMID 11907266</ref> | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 13:02, 21 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YOL027C |
| Gene name | MDM38 |
| Aliases | MKH1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:273725..272004 |
Description of YOL027C: Mitochondrial inner membrane protein, involved in membrane integration of a subset of mitochondrial proteins; required for K+/H+ exchange; associates with mitochondrial ribosomes; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome[1][2][3][4]
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References
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- ↑ Frazier AE, et al. (2006) Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery. J Cell Biol 172(4):553-64 SGD PMID 16476776
- ↑ Froschauer E, et al. (2005) Electroneutral K+/H+ exchange in mitochondrial membrane vesicles involves Yol027/Letm1 proteins. Biochim Biophys Acta 1711(1):41-8 SGD PMID 15904662
- ↑ Nowikovsky K, et al. (2004) The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome. J Biol Chem 279(29):30307-15 SGD PMID 15138253
- ↑ Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 SGD PMID 11907266
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