Difference between revisions of "YNL230C"

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'''Description of {{PAGENAME}}:''' Elongin A, F-box protein that forms a heterodimer with Elc1p and participates in transcription elongation<ref name='S000040848'>Botuyan MV, et al. (1999) Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C. Proc Natl Acad Sci U S A 96(16):9033-8
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'''Description of {{PAGENAME}}:''' Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21<ref name='S000120848'>Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA damaged yeast cells. Mol Cell Biol () {{SGDpaper|S000120848}} PMID 17296727</ref><ref name='S000040848'>Botuyan MV, et al. (1999) Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C. Proc Natl Acad Sci U S A 96(16):9033-8
 
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  {{SGDpaper|S000040848}} PMID 10430890</ref>
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 12:02, 21 February 2007

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Systematic name YNL230C
Gene name ELA1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:218663..217524


Description of YNL230C: Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21[1][2]




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References

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  1. Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA damaged yeast cells. Mol Cell Biol () SGD PMID 17296727
  2. Botuyan MV, et al. (1999) Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C. Proc Natl Acad Sci U S A 96(16):9033-8 SGD PMID 10430890

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