Difference between revisions of "YNL054W"

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'''Description of {{PAGENAME}}:''' Integral vacuolar membrane protein involved in vacuole inheritance and morphology; may function to regulate Fab1p kinase activity<ref name='S000069689'>Gary JD, et al. (2002) Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Mol Biol Cell 13(4):1238-51 {{SGDpaper|S000069689}} PMID 11950935</ref><ref name='S000048576'>Bonangelino CJ, et al. (1997) Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology. Mol Cell Biol 17(12):6847-58
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'''Description of {{PAGENAME}}:''' Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p kinase activity under basal conditions and also after hyperosmotic shock<ref name='S000114457'>Duex JE, et al. (2006) The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover. J Cell Biol 172(5):693-704 {{SGDpaper|S000114457}} PMID 16492811</ref><ref name='S000069689'>Gary JD, et al. (2002) Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Mol Biol Cell 13(4):1238-51 {{SGDpaper|S000069689}} PMID 11950935</ref><ref name='S000048576'>Bonangelino CJ, et al. (1997) Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology. Mol Cell Biol 17(12):6847-58
 
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  {{SGDpaper|S000048576}} PMID 9372916</ref>
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YNL054W
Gene name VAC7
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:526087..529584


Description of YNL054W: Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p kinase activity under basal conditions and also after hyperosmotic shock[1][2][3]




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References

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  1. Duex JE, et al. (2006) The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover. J Cell Biol 172(5):693-704 SGD PMID 16492811
  2. Gary JD, et al. (2002) Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Mol Biol Cell 13(4):1238-51 SGD PMID 11950935
  3. Bonangelino CJ, et al. (1997) Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology. Mol Cell Biol 17(12):6847-58 SGD PMID 9372916

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