Difference between revisions of "YMR260C"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YMR260C
Gene name TIF11
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:789838..789377


Description of YMR260C: Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3[1][2][3]




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References

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  1. Maag D, et al. (2005) A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon. Mol Cell 17(2):265-75 SGD PMID 15664195
  2. Olsen DS, et al. (2003) Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo. EMBO J 22(2):193-204 SGD PMID 12514125
  3. Wei CL, et al. (1995) Characterization of yeast translation initiation factor 1A and cloning of its essential gene. J Biol Chem 270(39):22788-94 SGD PMID 7559407

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