Difference between revisions of "YML106W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 12:02, 21 February 2007

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Systematic name YML106W
Gene name URA5
Aliases PYR5
Feature type ORF, Verified
Coordinates Chr XIII:56773..57453


Description of YML106W: One of two orotate phosphoribosyltransferase isozymes (see also URA10) that catalyze the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate[1][2][3]




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References

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  1. Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem (Tokyo) 70(2):249-62 SGD PMID 5094209
  2. Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 SGD PMID 371963
  3. de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62 SGD PMID 2651891

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