Difference between revisions of "YNL176C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005120 YNL176C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TDA7 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TDA7 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XIV: | + | |nowrap| Chr XIV:306980..305070 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005120 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005120 | ||
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| − | '''Description of YNL176C:''' Cell cycle-regulated gene of unknown function, promoter bound by Fkh2p<ref name='S000087197'>de Lichtenberg U, et al. (2005) New weakly expressed cell cycle-regulated genes in yeast. Yeast 22(15):1191-201 | + | '''Description of YNL176C:''' Cell cycle-regulated gene of unknown function, promoter bound by Fkh2p; null mutant is sensitive to expression of the top1-T722A allele<ref name='S000142390'>Reid RJ, et al. (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86 {{SGDpaper|S000142390}} PMID 21173034</ref><ref name='S000087197'>de Lichtenberg U, et al. (2005) New weakly expressed cell cycle-regulated genes in yeast. Yeast 22(15):1191-201 |
{{SGDpaper|S000087197}} PMID 16278933</ref> | {{SGDpaper|S000087197}} PMID 16278933</ref> | ||
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{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | == Transmembrane Domain GxxxG == | ||
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| + | The transmembrane domain of Tda7p shows homology with the SKG6/AXL2 alpha-helix transmembrane domain (IPR014805). In particular, this domain contains GtivGsvvGsvgG. The presence of multiple, chained GxxxG motifs <ref name='PMID 15313242'> Senes A, Engel DE and DeGrado WF (2004) Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs. Curr Opin Struct Biol. 2004 14(4):465-79. PMID 15313242</ref> strongly indicates that Tda7p multimerises. | ||
Latest revision as of 08:17, 21 March 2013
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| Systematic name | YNL176C |
| Gene name | TDA7 |
| Aliases | |
| Feature type | ORF, Uncharacterized |
| Coordinates | Chr XIV:306980..305070 |
| Primary SGDID | S000005120 |
Description of YNL176C: Cell cycle-regulated gene of unknown function, promoter bound by Fkh2p; null mutant is sensitive to expression of the top1-T722A allele[1][2]
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Community Commentary
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Transmembrane Domain GxxxG
The transmembrane domain of Tda7p shows homology with the SKG6/AXL2 alpha-helix transmembrane domain (IPR014805). In particular, this domain contains GtivGsvvGsvgG. The presence of multiple, chained GxxxG motifs [3] strongly indicates that Tda7p multimerises.
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References
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- ↑ Reid RJ, et al. (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86 SGD PMID 21173034
- ↑ de Lichtenberg U, et al. (2005) New weakly expressed cell cycle-regulated genes in yeast. Yeast 22(15):1191-201 SGD PMID 16278933
- ↑ Senes A, Engel DE and DeGrado WF (2004) Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs. Curr Opin Struct Biol. 2004 14(4):465-79. PMID 15313242
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