Difference between revisions of "YHL033C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YHL033C YHL033C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001025 YHL033C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPL8A ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPL8A ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
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|nowrap| Chr VIII:36023..35253
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|nowrap| Chr VIII:36025..35255
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001025
 
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'''Description of {{PAGENAME}}:''' Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Bp and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits<ref name='S000074367'>Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 {{SGDpaper|S000074367}} PMID 12490706</ref><ref name='S000058461'>Planta RJ and Mager WH (1998) The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14(5):471-7 {{SGDpaper|S000058461}} PMID 9559554</ref><ref name='S000056784'>Arevalo SG and Warner JR (1990) Ribosomal protein L4 of Saccharomyces cerevisiae: the gene and its protein. Nucleic Acids Res 18(6):1447-9 {{SGDpaper|S000056784}} PMID 2183194</ref><ref name='S000056729'>Yon J, et al. (1991) The organization and expression of the Saccharomyces cerevisiae L4 ribosomal protein genes and their identification as the homologues of the mammalian ribosomal protein gene L7a. Mol Gen Genet 227(1):72-80 {{SGDpaper|S000056729}} PMID 2046660</ref><ref name='S000050422'>Ohtake Y and Wickner RB (1995) Yeast virus propagation depends critically on free 60S ribosomal subunit concentration. Mol Cell Biol 15(5):2772-81
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'''Description of YHL033C:''' Ribosomal 60S subunit protein L8A; mutation results in decreased amounts of free 60S subunits; homologous to mammalian ribosomal protein L7A, no bacterial homolog; RPL8A has a paralog, RPL8B, that arose from the whole genome duplication<ref name='S000056784'>Arevalo SG and Warner JR (1990) Ribosomal protein L4 of Saccharomyces cerevisiae: the gene and its protein. Nucleic Acids Res 18(6):1447-9 {{SGDpaper|S000056784}} PMID 2183194</ref><ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000150523'>Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol () {{SGDpaper|S000150523}} PMID 22884264</ref><ref name='S000074367'>Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 {{SGDpaper|S000074367}} PMID 12490706</ref><ref name='S000050422'>Ohtake Y and Wickner RB (1995) Yeast virus propagation depends critically on free 60S ribosomal subunit concentration. Mol Cell Biol 15(5):2772-81 {{SGDpaper|S000050422}} PMID 7739558</ref><ref name='S000058461'>Planta RJ and Mager WH (1998) The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14(5):471-7 {{SGDpaper|S000058461}} PMID 9559554</ref><ref name='S000056729'>Yon J, et al. (1991) The organization and expression of the Saccharomyces cerevisiae L4 ribosomal protein genes and their identification as the homologues of the mammalian ribosomal protein gene L7a. Mol Gen Genet 227(1):72-80
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{{SGDpaper|S000056729}} PMID 2046660</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 13:05, 22 October 2012

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Systematic name YHL033C
Gene name RPL8A
Aliases MAK7
Feature type ORF, Verified
Coordinates Chr VIII:36025..35255
Primary SGDID S000001025


Description of YHL033C: Ribosomal 60S subunit protein L8A; mutation results in decreased amounts of free 60S subunits; homologous to mammalian ribosomal protein L7A, no bacterial homolog; RPL8A has a paralog, RPL8B, that arose from the whole genome duplication[1][2][3][4][5][6][7]




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References

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  1. ↑ Arevalo SG and Warner JR (1990) Ribosomal protein L4 of Saccharomyces cerevisiae: the gene and its protein. Nucleic Acids Res 18(6):1447-9 SGD PMID 2183194
  2. ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  3. ↑ Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol () SGD PMID 22884264
  4. ↑ Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 SGD PMID 12490706
  5. ↑ Ohtake Y and Wickner RB (1995) Yeast virus propagation depends critically on free 60S ribosomal subunit concentration. Mol Cell Biol 15(5):2772-81 SGD PMID 7739558
  6. ↑ Planta RJ and Mager WH (1998) The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14(5):471-7 SGD PMID 9559554
  7. ↑ Yon J, et al. (1991) The organization and expression of the Saccharomyces cerevisiae L4 ribosomal protein genes and their identification as the homologues of the mammalian ribosomal protein gene L7a. Mol Gen Genet 227(1):72-80 SGD PMID 2046660

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