Difference between revisions of "YMR120C"
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− | '''Description of YMR120C:''' Enzyme of 'de novo' purine biosynthesis | + | '''Description of YMR120C:''' Enzyme of 'de novo' purine biosynthesis; contains both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities; ADE17 has a paralog, ADE16, that arose from the whole genome duplication; ade16 ade17 mutants require adenine and histidine<ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000053260'>Tibbetts AS and Appling DR (2000) Characterization of two 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase isozymes from Saccharomyces cerevisiae. J Biol Chem 275(27):20920-7 |
{{SGDpaper|S000053260}} PMID 10877846</ref> | {{SGDpaper|S000053260}} PMID 10877846</ref> | ||
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Latest revision as of 13:05, 12 October 2012
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Systematic name | YMR120C |
Gene name | ADE17 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XIII:509280..507502 |
Primary SGDID | S000004727 |
Description of YMR120C: Enzyme of 'de novo' purine biosynthesis; contains both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities; ADE17 has a paralog, ADE16, that arose from the whole genome duplication; ade16 ade17 mutants require adenine and histidine[1][2]
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References
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- ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
- ↑ Tibbetts AS and Appling DR (2000) Characterization of two 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase isozymes from Saccharomyces cerevisiae. J Biol Chem 275(27):20920-7 SGD PMID 10877846
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