Difference between revisions of "YML001W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004460 YML001W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''YPT7 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''YPT7 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XIII:267174..267800 | |nowrap| Chr XIII:267174..267800 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004460 | ||
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| − | '''Description of | + | '''Description of YML001W:''' Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion; interacts with the cargo selection/retromer complex for retrograde sorting; similar to mammalian Rab7<ref name='S000082010'>Collins KM, et al. (2005) Sec17p and HOPS, in distinct SNARE complexes, mediate SNARE complex disruption or assembly for fusion. EMBO J 24(10):1775-86 {{SGDpaper|S000082010}} PMID 15889152</ref><ref name='S000051599'>Haas A, et al. (1995) The GTPase Ypt7p of Saccharomyces cerevisiae is required on both partner vacuoles for the homotypic fusion step of vacuole inheritance. EMBO J 14(21):5258-70 {{SGDpaper|S000051599}} PMID 7489715</ref><ref name='S000150825'>Liu TT, et al. (2012) Rab GTPase regulation of retromer-mediated cargo export during endosome maturation. Mol Biol Cell 23(13):2505-15 {{SGDpaper|S000150825}} PMID 22593205</ref><ref name='S000039543'>Schimmoller F and Riezman H (1993) Involvement of Ypt7p, a small GTPase, in traffic from late endosome to the vacuole in yeast. J Cell Sci 106 ( Pt 3):823-30 {{SGDpaper|S000039543}} PMID 8308065</ref><ref name='S000054804'>Wichmann H, et al. (1992) Endocytosis in yeast: evidence for the involvement of a small GTP-binding protein (Ypt7p). Cell 71(7):1131-42 |
| − | {{SGDpaper| | + | {{SGDpaper|S000054804}} PMID 1473149</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 13:05, 26 September 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YML001W |
| Gene name | YPT7 |
| Aliases | AST4, VAM4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:267174..267800 |
| Primary SGDID | S000004460 |
Description of YML001W: Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion; interacts with the cargo selection/retromer complex for retrograde sorting; similar to mammalian Rab7[1][2][3][4][5]
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References
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- ↑ Collins KM, et al. (2005) Sec17p and HOPS, in distinct SNARE complexes, mediate SNARE complex disruption or assembly for fusion. EMBO J 24(10):1775-86 SGD PMID 15889152
- ↑ Haas A, et al. (1995) The GTPase Ypt7p of Saccharomyces cerevisiae is required on both partner vacuoles for the homotypic fusion step of vacuole inheritance. EMBO J 14(21):5258-70 SGD PMID 7489715
- ↑ Liu TT, et al. (2012) Rab GTPase regulation of retromer-mediated cargo export during endosome maturation. Mol Biol Cell 23(13):2505-15 SGD PMID 22593205
- ↑ Schimmoller F and Riezman H (1993) Involvement of Ypt7p, a small GTPase, in traffic from late endosome to the vacuole in yeast. J Cell Sci 106 ( Pt 3):823-30 SGD PMID 8308065
- ↑ Wichmann H, et al. (1992) Endocytosis in yeast: evidence for the involvement of a small GTP-binding protein (Ypt7p). Cell 71(7):1131-42 SGD PMID 1473149
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