Difference between revisions of "YNL302C"
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| − | '''Description of YNL302C:''' Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; | + | '''Description of YNL302C:''' Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; homologous to mammalian ribosomal protein S19, no bacterial homolog; mutations in human RPS19 are associated with Diamond Blackfan anemia; RPS19B has a paralog, RPS19A, that arose from the whole genome duplication<ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000150523'>Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol () {{SGDpaper|S000150523}} PMID 22884264</ref><ref name='S000074367'>Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 {{SGDpaper|S000074367}} PMID 12490706</ref><ref name='S000086728'>Leger-Silvestre I, et al. (2005) Specific Role for Yeast Homologs of the Diamond Blackfan Anemia-associated Rps19 Protein in Ribosome Synthesis. J Biol Chem 280(46):38177-85 |
{{SGDpaper|S000086728}} PMID 16159874</ref> | {{SGDpaper|S000086728}} PMID 16159874</ref> | ||
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Latest revision as of 13:05, 20 September 2012
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| Systematic name | YNL302C |
| Gene name | RPS19B |
| Aliases | RP55B |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:62943..61958 |
| Primary SGDID | S000005246 |
Description of YNL302C: Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; homologous to mammalian ribosomal protein S19, no bacterial homolog; mutations in human RPS19 are associated with Diamond Blackfan anemia; RPS19B has a paralog, RPS19A, that arose from the whole genome duplication[1][2][3][4]
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References
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- ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
- ↑ Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol () SGD PMID 22884264
- ↑ Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 SGD PMID 12490706
- ↑ Leger-Silvestre I, et al. (2005) Specific Role for Yeast Homologs of the Diamond Blackfan Anemia-associated Rps19 Protein in Ribosome Synthesis. J Biol Chem 280(46):38177-85 SGD PMID 16159874
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