Difference between revisions of "YEL034W"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
(Automated import of articles)
 
(13 intermediate revisions by the same user not shown)
Line 4: Line 4:
 
{|{{Prettytable}} align = 'right' width = '200px'
 
{|{{Prettytable}} align = 'right' width = '200px'
 
|-
 
|-
−
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YEL034W YEL034W]  
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000760 YEL034W]  
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HYP2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HYP2 ''
 
|-
 
|-
−
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''TIF51A''
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''TIF51A, eIF-5A, eIF5A''
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
Line 14: Line 14:
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr V:85676..86149
 
|nowrap| Chr V:85676..86149
 +
|-
 +
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000760
 
|}
 
|}
 
<br>
 
<br>
−
'''Description of {{PAGENAME}}:''' Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Anb1p; possible role in translation elongation; undergoes an essential hypusination modification<ref name='S000117998'>Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66 {{SGDpaper|S000117998}} PMID 16914118</ref><ref name='S000069868'>Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 {{SGDpaper|S000069868}} PMID 11861547</ref><ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25
+
'''Description of YEL034W:''' Translation elongation factor eIF-5A; may function in translation initiation; structural homolog of bacterial EF-P; undergoes an essential hypusination modification; HYP2 has a paralog, ANB1, that arose from the whole genome duplication<ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000129817'>Gregio AP, et al. (2009) eIF5A has a function in the elongation step of translation in yeast. Biochem Biophys Res Commun 380(4):785-90 {{SGDpaper|S000129817}} PMID 19338753</ref><ref name='S000144853'>Henderson A and Hershey JW (2011) Eukaryotic translation initiation factor (eIF) 5A stimulates protein synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(16):6415-9 {{SGDpaper|S000144853}} PMID 21451136</ref><ref name='S000130229'>Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 {{SGDpaper|S000130229}} PMID 19424157</ref><ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 {{SGDpaper|S000040125}} PMID 8314769</ref><ref name='S000069868'>Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 {{SGDpaper|S000069868}} PMID 11861547</ref><ref name='S000117998'>Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66
−
  {{SGDpaper|S000040125}} PMID 8314769</ref>
+
  {{SGDpaper|S000117998}} PMID 16914118</ref>
 
<br>
 
<br>
 
<br>
 
<br>
Line 27: Line 29:
 
==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
{{CommentaryHelp}}
 +
 +
 +
 +
 +
<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
 +
<!--
 +
Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
 +
<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
 +
J Biol Chem 278(5):3265-74</ref>
 +
-->
 +
  
  

Latest revision as of 13:05, 20 September 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YEL034W
Gene name HYP2
Aliases TIF51A, eIF-5A, eIF5A
Feature type ORF, Verified
Coordinates Chr V:85676..86149
Primary SGDID S000000760


Description of YEL034W: Translation elongation factor eIF-5A; may function in translation initiation; structural homolog of bacterial EF-P; undergoes an essential hypusination modification; HYP2 has a paralog, ANB1, that arose from the whole genome duplication[1][2][3][4][5][6][7]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  2. ↑ Gregio AP, et al. (2009) eIF5A has a function in the elongation step of translation in yeast. Biochem Biophys Res Commun 380(4):785-90 SGD PMID 19338753
  3. ↑ Henderson A and Hershey JW (2011) Eukaryotic translation initiation factor (eIF) 5A stimulates protein synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(16):6415-9 SGD PMID 21451136
  4. ↑ Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 SGD PMID 19424157
  5. ↑ Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 SGD PMID 8314769
  6. ↑ Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 SGD PMID 11861547
  7. ↑ Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66 SGD PMID 16914118

See Help:Categories on how to add the wiki page for this gene to a Category </protect>

Retrieved from "https://wiki.yeastgenome.org/index.php?title=YEL034W&oldid=392604"