Difference between revisions of "YMR044W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004647 YMR044W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''IOC4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''IOC4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr XIII: | + | |nowrap| Chr XIII:355384..356811 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004647 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004647 | ||
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− | '''Description of YMR044W:''' Member of a complex (Isw1b) with Isw1p and Ioc2p | + | '''Description of YMR044W:''' Member of a complex (Isw1b) with Isw1p and Ioc2p; interacts directly with H3K36me3 nucleosomes through its PWWP domain to recruit the Isw1b complex to open reading frames in a Set2p-dependent manner; Isw1b exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing<ref name='S000075399'>Morillon A, et al. (2003) Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II. Cell 115(4):425-35 {{SGDpaper|S000075399}} PMID 14622597</ref><ref name='S000150705'>Smolle M, et al. (2012) Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange.LID - 10.1038/nsmb.2312 [doi] Nat Struct Mol Biol () {{SGDpaper|S000150705}} PMID 22922743</ref><ref name='S000072478'>Vary JC Jr, et al. (2003) Yeast Isw1p forms two separable complexes in vivo. Mol Cell Biol 23(1):80-91 |
{{SGDpaper|S000072478}} PMID 12482963</ref> | {{SGDpaper|S000072478}} PMID 12482963</ref> | ||
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Latest revision as of 14:05, 18 September 2012
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Systematic name | YMR044W |
Gene name | IOC4 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XIII:355384..356811 |
Primary SGDID | S000004647 |
Description of YMR044W: Member of a complex (Isw1b) with Isw1p and Ioc2p; interacts directly with H3K36me3 nucleosomes through its PWWP domain to recruit the Isw1b complex to open reading frames in a Set2p-dependent manner; Isw1b exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing[1][2][3]
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References
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- ↑ Morillon A, et al. (2003) Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II. Cell 115(4):425-35 SGD PMID 14622597
- ↑ Smolle M, et al. (2012) Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange.LID - 10.1038/nsmb.2312 [doi] Nat Struct Mol Biol () SGD PMID 22922743
- ↑ Vary JC Jr, et al. (2003) Yeast Isw1p forms two separable complexes in vivo. Mol Cell Biol 23(1):80-91 SGD PMID 12482963
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