Difference between revisions of "YKL204W"
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{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001687 YKL204W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''EAP1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''EAP1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr XI: | + | |nowrap| Chr XI:53704..55602 |
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+ | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001687 | ||
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<br> | <br> | ||
− | '''Description of | + | '''Description of YKL204W:''' eIF4E-associated protein, competes with eIF4G for binding to eIF4E; accelerates mRNA degradation by promoting decapping, facilitated by interaction with eIF4E; essential for Puf5p mediated repression; associates with Puf5p and Dhh1p; inhibits cap-dependent translation; functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade<ref name='S000150503'>Blewett NH and Goldstrohm AC (2012) An eIF4E-binding protein promotes mRNA decapping and is required for PUF repression. Mol Cell Biol () {{SGDpaper|S000150503}} PMID 22890846</ref><ref name='S000059777'>Chial HJ, et al. (2000) Yeast Eap1p, an eIF4E-associated protein, has a separate function involving genetic stability. Curr Biol 10(23):1519-22 {{SGDpaper|S000059777}} PMID 11114520</ref><ref name='S000043142'>Cosentino GP, et al. (2000) Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae. Mol Cell Biol 20(13):4604-13 |
{{SGDpaper|S000043142}} PMID 10848587</ref> | {{SGDpaper|S000043142}} PMID 10848587</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> |
Latest revision as of 14:05, 28 August 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YKL204W |
Gene name | EAP1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XI:53704..55602 |
Primary SGDID | S000001687 |
Description of YKL204W: eIF4E-associated protein, competes with eIF4G for binding to eIF4E; accelerates mRNA degradation by promoting decapping, facilitated by interaction with eIF4E; essential for Puf5p mediated repression; associates with Puf5p and Dhh1p; inhibits cap-dependent translation; functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade[1][2][3]
</protect>
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References
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- ↑ Blewett NH and Goldstrohm AC (2012) An eIF4E-binding protein promotes mRNA decapping and is required for PUF repression. Mol Cell Biol () SGD PMID 22890846
- ↑ Chial HJ, et al. (2000) Yeast Eap1p, an eIF4E-associated protein, has a separate function involving genetic stability. Curr Biol 10(23):1519-22 SGD PMID 11114520
- ↑ Cosentino GP, et al. (2000) Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae. Mol Cell Biol 20(13):4604-13 SGD PMID 10848587
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