Difference between revisions of "YBR186W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YBR186W YBR186W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000390 YBR186W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PCH2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PCH2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr II:600548..602355
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|nowrap| Chr II:600553..602360
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000390
 
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'''Description of {{PAGENAME}}:''' Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in the rDNA<ref name='S000059155'>San-Segundo PA and Roeder GS (2000) Role for the silencing protein Dot1 in meiotic checkpoint control. Mol Biol Cell 11(10):3601-15 {{SGDpaper|S000059155}} PMID 11029058</ref><ref name='S000043670'>San-Segundo PA and Roeder GS (1999) Pch2 links chromatin silencing to meiotic checkpoint control. Cell 97(3):313-24
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'''Description of YBR186W:''' Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in the rDNA; required for meiotic double-stranded break formation<ref name='S000150088'>Farmer S, et al. (2012) Budding yeast pch2, a widely conserved meiotic protein, is involved in the initiation of meiotic recombination. PLoS One 7(6):e39724 {{SGDpaper|S000150088}} PMID 22745819</ref><ref name='S000043670'>San-Segundo PA and Roeder GS (1999) Pch2 links chromatin silencing to meiotic checkpoint control. Cell 97(3):313-24 {{SGDpaper|S000043670}} PMID 10319812</ref><ref name='S000059155'>San-Segundo PA and Roeder GS (2000) Role for the silencing protein Dot1 in meiotic checkpoint control. Mol Biol Cell 11(10):3601-15
  {{SGDpaper|S000043670}} PMID 10319812</ref>
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  {{SGDpaper|S000059155}} PMID 11029058</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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<!--
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 13:05, 19 July 2012

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Systematic name YBR186W
Gene name PCH2
Aliases
Feature type ORF, Verified
Coordinates Chr II:600553..602360
Primary SGDID S000000390


Description of YBR186W: Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in the rDNA; required for meiotic double-stranded break formation[1][2][3]




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References

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  1. Farmer S, et al. (2012) Budding yeast pch2, a widely conserved meiotic protein, is involved in the initiation of meiotic recombination. PLoS One 7(6):e39724 SGD PMID 22745819
  2. San-Segundo PA and Roeder GS (1999) Pch2 links chromatin silencing to meiotic checkpoint control. Cell 97(3):313-24 SGD PMID 10319812
  3. San-Segundo PA and Roeder GS (2000) Role for the silencing protein Dot1 in meiotic checkpoint control. Mol Biol Cell 11(10):3601-15 SGD PMID 11029058

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