Difference between revisions of "YBR073W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000277 YBR073W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RDH54 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RDH54 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr II: | + | |nowrap| Chr II:383112..385988 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000277 | ||
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| − | '''Description of | + | '''Description of YBR073W:''' DNA-dependent ATPase; stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference; interacts with Dmc1p; stimulates Dmc1p and Rad51p<ref name='S000055507'>Dresser ME, et al. (1997) DMC1 functions in a Saccharomyces cerevisiae meiotic pathway that is largely independent of the RAD51 pathway. Genetics 147(2):533-44 {{SGDpaper|S000055507}} PMID 9335591</ref><ref name='S000041985'>Klein HL (1997) RDH54, a RAD54 homologue in Saccharomyces cerevisiae, is required for mitotic diploid-specific recombination and repair and for meiosis. Genetics 147(4):1533-43 {{SGDpaper|S000041985}} PMID 9409819</ref><ref name='S000150037'>Nimonkar AV, et al. (2012) Saccharomyces cerevisiae Dmc1 and Rad51 preferentially function with Tid1 and Rad54, respectively, to promote DNA strand invasion during genetic recombination. J Biol Chem () {{SGDpaper|S000150037}} PMID 22761450</ref><ref name='S000046962'>Petukhova G, et al. (2000) Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1. Genes Dev 14(17):2206-15 {{SGDpaper|S000046962}} PMID 10970884</ref><ref name='S000073076'>Shinohara M, et al. (2003) Crossover interference in Saccharomyces cerevisiae requires a TID1/RDH54- and DMC1-dependent pathway. Genetics 163(4):1273-86 |
| − | {{SGDpaper| | + | {{SGDpaper|S000073076}} PMID 12702674</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 13:05, 16 July 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBR073W |
| Gene name | RDH54 |
| Aliases | TID1 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:383112..385988 |
| Primary SGDID | S000000277 |
Description of YBR073W: DNA-dependent ATPase; stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference; interacts with Dmc1p; stimulates Dmc1p and Rad51p[1][2][3][4][5]
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Community Commentary
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References
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- ↑ Dresser ME, et al. (1997) DMC1 functions in a Saccharomyces cerevisiae meiotic pathway that is largely independent of the RAD51 pathway. Genetics 147(2):533-44 SGD PMID 9335591
- ↑ Klein HL (1997) RDH54, a RAD54 homologue in Saccharomyces cerevisiae, is required for mitotic diploid-specific recombination and repair and for meiosis. Genetics 147(4):1533-43 SGD PMID 9409819
- ↑ Nimonkar AV, et al. (2012) Saccharomyces cerevisiae Dmc1 and Rad51 preferentially function with Tid1 and Rad54, respectively, to promote DNA strand invasion during genetic recombination. J Biol Chem () SGD PMID 22761450
- ↑ Petukhova G, et al. (2000) Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1. Genes Dev 14(17):2206-15 SGD PMID 10970884
- ↑ Shinohara M, et al. (2003) Crossover interference in Saccharomyces cerevisiae requires a TID1/RDH54- and DMC1-dependent pathway. Genetics 163(4):1273-86 SGD PMID 12702674
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