Difference between revisions of "YAR002W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000063 YAR002W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NUP60 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NUP60 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr I: | + | |nowrap| Chr I:152257..153876 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000063 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000063 | ||
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| − | '''Description of YAR002W:''' | + | '''Description of YAR002W:''' FG-nucleoporin component of central core of the nuclear pore complex (NPC); contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier and is involved in gene tethering at the nuclear periphery; both NUP1 and NUP60 are homologous to human NUP153<ref name='S000061454'>Allen NP, et al. (2001) Proteomic analysis of nucleoporin interacting proteins. J Biol Chem 276(31):29268-74 {{SGDpaper|S000061454}} PMID 11387327</ref><ref name='S000061235'>Denning D, et al. (2001) The nucleoporin Nup60p functions as a Gsp1p-GTP-sensitive tether for Nup2p at the nuclear pore complex. J Cell Biol 154(5):937-50 {{SGDpaper|S000061235}} PMID 11535617</ref><ref name='S000135178'>Fernandez-Martinez J and Rout MP (2009) Nuclear pore complex biogenesis. Curr Opin Cell Biol 21(4):603-12 {{SGDpaper|S000135178}} PMID 19524430</ref><ref name='S000071494'>Feuerbach F, et al. (2002) Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast. Nat Cell Biol 4(3):214-21 {{SGDpaper|S000071494}} PMID 11862215</ref><ref name='S000138391'>Light WH, et al. (2010) Interaction of a DNA Zip code with the nuclear pore complex promotes H2A.Z incorporation and INO1 transcriptional memory. Mol Cell 40(1):112-25 {{SGDpaper|S000138391}} PMID 20932479</ref><ref name='S000122438'>Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96 {{SGDpaper|S000122438}} PMID 17418788</ref><ref name='S000139600'>Powrie EA, et al. (2011) A nucleoporin, Nup60p, affects the nuclear and cytoplasmic localization of ASH1 mRNA in S. cerevisiae. RNA 17(1):134-44 {{SGDpaper|S000139600}} PMID 21036941</ref><ref name='S000075845'>Strawn LA, et al. (2004) Minimal nuclear pore complexes define FG repeat domains essential for transport. Nat Cell Biol 6(3):197-206 |
| − | {{SGDpaper| | + | {{SGDpaper|S000075845}} PMID 15039779</ref> |
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Latest revision as of 13:05, 19 June 2012
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| Systematic name | YAR002W |
| Gene name | NUP60 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr I:152257..153876 |
| Primary SGDID | S000000063 |
Description of YAR002W: FG-nucleoporin component of central core of the nuclear pore complex (NPC); contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier and is involved in gene tethering at the nuclear periphery; both NUP1 and NUP60 are homologous to human NUP153[1][2][3][4][5][6][7][8]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [9] [10]
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References
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- ↑ Allen NP, et al. (2001) Proteomic analysis of nucleoporin interacting proteins. J Biol Chem 276(31):29268-74 SGD PMID 11387327
- ↑ Denning D, et al. (2001) The nucleoporin Nup60p functions as a Gsp1p-GTP-sensitive tether for Nup2p at the nuclear pore complex. J Cell Biol 154(5):937-50 SGD PMID 11535617
- ↑ Fernandez-Martinez J and Rout MP (2009) Nuclear pore complex biogenesis. Curr Opin Cell Biol 21(4):603-12 SGD PMID 19524430
- ↑ Feuerbach F, et al. (2002) Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast. Nat Cell Biol 4(3):214-21 SGD PMID 11862215
- ↑ Light WH, et al. (2010) Interaction of a DNA Zip code with the nuclear pore complex promotes H2A.Z incorporation and INO1 transcriptional memory. Mol Cell 40(1):112-25 SGD PMID 20932479
- ↑ Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96 SGD PMID 17418788
- ↑ Powrie EA, et al. (2011) A nucleoporin, Nup60p, affects the nuclear and cytoplasmic localization of ASH1 mRNA in S. cerevisiae. RNA 17(1):134-44 SGD PMID 21036941
- ↑ Strawn LA, et al. (2004) Minimal nuclear pore complexes define FG repeat domains essential for transport. Nat Cell Biol 6(3):197-206 SGD PMID 15039779
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-21
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