Difference between revisions of "YGL248W"
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 13:02, 21 February 2007
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Systematic name | YGL248W |
Gene name | PDE1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VII:35653..36762 |
Description of YGL248W: Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation[1][2][3][4][5]
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Contents
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References
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- ↑ Wera S, et al. (1997) Glucose exerts opposite effects on mRNA versus protein and activity levels of Pde1, the low-affinity cAMP phosphodiesterase from budding yeast, Saccharomyces cerevisiae. FEBS Lett 420(2-3):147-50 SGD PMID 9459299
- ↑ Ma P, et al. (1999) The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signaling. Mol Biol Cell 10(1):91-104 SGD PMID 9880329
- ↑ Uno I, et al. (1983) Characterization of a cyclic nucleotide phosphodiesterase-deficient mutant in yeast. J Biol Chem 258(6):3539-42 SGD PMID 6300049
- ↑ Thevelein JM and de Winde JH (1999) Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol 33(5):904-18 SGD PMID 10476026
- ↑ Nikawa J, et al. (1987) Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae. Mol Cell Biol 7(10):3629-36 SGD PMID 2824992
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