Difference between revisions of "YGL241W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003210 YGL241W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''KAP114 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''KAP114 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr VII:45445..48459 | |nowrap| Chr VII:45445..48459 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003210 | ||
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| − | '''Description of | + | '''Description of YGL241W:''' Karyopherin, responsible for nuclear import of specific proteins; cargoes include Spt15p, Sua7p, histones H2A and H2B, and Nap1p; amino terminus shows similarity to those of other importins, particularly Cse1p; localization is primarily nuclear; function is regulated by sumoylation<ref name='S000082013'>Hodges JL, et al. (2005) Nuclear import of TFIIB is mediated by Kap114p, a karyopherin with multiple cargo-binding domains. Mol Biol Cell 16(7):3200-10 {{SGDpaper|S000082013}} PMID 15888545</ref><ref name='S000061910'>Morehouse H, et al. (1999) The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein. Proc Natl Acad Sci U S A 96(22):12542-7 {{SGDpaper|S000061910}} PMID 10535958</ref><ref name='S000075933'>Mosammaparast N, et al. (2002) A role for nucleosome assembly protein 1 in the nuclear transport of histones H2A and H2B. EMBO J 21(23):6527-38 {{SGDpaper|S000075933}} PMID 12456659</ref><ref name='S000149483'>Rothenbusch U, et al. (2012) Sumoylation regulates Kap114-mediated nuclear transport.LID - 10.1038/emboj.2012.102 [doi] EMBO J () |
| − | {{SGDpaper| | + | {{SGDpaper|S000149483}} PMID 22562154</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 14:05, 6 June 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGL241W |
| Gene name | KAP114 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:45445..48459 |
| Primary SGDID | S000003210 |
Description of YGL241W: Karyopherin, responsible for nuclear import of specific proteins; cargoes include Spt15p, Sua7p, histones H2A and H2B, and Nap1p; amino terminus shows similarity to those of other importins, particularly Cse1p; localization is primarily nuclear; function is regulated by sumoylation[1][2][3][4]
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Contents
Community Commentary
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References
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- ↑ Hodges JL, et al. (2005) Nuclear import of TFIIB is mediated by Kap114p, a karyopherin with multiple cargo-binding domains. Mol Biol Cell 16(7):3200-10 SGD PMID 15888545
- ↑ Morehouse H, et al. (1999) The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein. Proc Natl Acad Sci U S A 96(22):12542-7 SGD PMID 10535958
- ↑ Mosammaparast N, et al. (2002) A role for nucleosome assembly protein 1 in the nuclear transport of histones H2A and H2B. EMBO J 21(23):6527-38 SGD PMID 12456659
- ↑ Rothenbusch U, et al. (2012) Sumoylation regulates Kap114-mediated nuclear transport.LID - 10.1038/emboj.2012.102 [doi] EMBO J () SGD PMID 22562154
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