Difference between revisions of "YFL010C"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YFL010C
Gene name WWM1
Aliases
Feature type ORF, Verified
Coordinates Chr VI:115737..115102


Description of YFL010C: WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes Gi phase growth arrest and clonal death that is suppressed by overexpression of MCA1[1][2][3][4]




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References

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  1. Stevenson LF, et al. (2001) A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc Natl Acad Sci U S A 98(7):3946-51 SGD PMID 11274415
  2. Madeo F, et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol Cell 9(4):911-7 SGD PMID 11983181
  3. Szallies A, et al. (2002) A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae. FEBS Lett 517(1-3):144-50 SGD PMID 12062425
  4. Uetz P, et al. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403(6770):623-7 SGD PMID 10688190

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