Difference between revisions of "YMR228W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004841 YMR228W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MTF1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MTF1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr XIII: | + | |nowrap| Chr XIII:724626..725651 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004841 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004841 | ||
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− | '''Description of YMR228W:''' Mitochondrial RNA polymerase specificity factor | + | '''Description of YMR228W:''' Mitochondrial RNA polymerase specificity factor; has structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors; Mtf1p interacts with and stabilizes the Rpo41p-promoter complex, enhancing DNA bending and melting to facilitate pre-initiation open complex formation<ref name='S000039346'>Mangus DA, et al. (1994) Release of the yeast mitochondrial RNA polymerase specificity factor from transcription complexes. J Biol Chem 269(42):26568-74 {{SGDpaper|S000039346}} PMID 7929382</ref><ref name='S000079841'>Matsunaga M and Jaehning JA (2004) Intrinsic promoter recognition by a core RNA polymerase. J Biol Chem 279(43):44239-42 {{SGDpaper|S000079841}} PMID 15342628</ref><ref name='S000067659'>Schubot FD, et al. (2001) Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription. Protein Sci 10(10):1980-8 {{SGDpaper|S000067659}} PMID 11567089</ref><ref name='S000146745'>Tang GQ, et al. (2011) Transcription factor-dependent DNA bending governs promoter recognition by the mitochondrial RNA polymerase. J Biol Chem () {{SGDpaper|S000146745}} PMID 21911502</ref><ref name='S000149299'>Velazquez G, et al. (2012) Conservation of Promoter Melting Mechanisms in Divergent Regions of the Single-Subunit RNA Polymerases. Biochemistry () |
− | {{SGDpaper| | + | {{SGDpaper|S000149299}} PMID 22524540</ref> |
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Latest revision as of 14:05, 9 May 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YMR228W |
Gene name | MTF1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XIII:724626..725651 |
Primary SGDID | S000004841 |
Description of YMR228W: Mitochondrial RNA polymerase specificity factor; has structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors; Mtf1p interacts with and stabilizes the Rpo41p-promoter complex, enhancing DNA bending and melting to facilitate pre-initiation open complex formation[1][2][3][4][5]
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References
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- ↑ Mangus DA, et al. (1994) Release of the yeast mitochondrial RNA polymerase specificity factor from transcription complexes. J Biol Chem 269(42):26568-74 SGD PMID 7929382
- ↑ Matsunaga M and Jaehning JA (2004) Intrinsic promoter recognition by a core RNA polymerase. J Biol Chem 279(43):44239-42 SGD PMID 15342628
- ↑ Schubot FD, et al. (2001) Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription. Protein Sci 10(10):1980-8 SGD PMID 11567089
- ↑ Tang GQ, et al. (2011) Transcription factor-dependent DNA bending governs promoter recognition by the mitochondrial RNA polymerase. J Biol Chem () SGD PMID 21911502
- ↑ Velazquez G, et al. (2012) Conservation of Promoter Melting Mechanisms in Divergent Regions of the Single-Subunit RNA Polymerases. Biochemistry () SGD PMID 22524540
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