Difference between revisions of "YML035C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004498 YML035C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''AMD1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''AMD1 '' | ||
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|nowrap| Chr XIII:208860..206428 | |nowrap| Chr XIII:208860..206428 | ||
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− | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004498 |
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− | '''Description of | + | '''Description of YML035C:''' AMP deaminase; tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; thought to be involved in regulation of intracellular purine (adenine, guanine, and inosine) nucleotide pools<ref name='S000126196'>Gauthier S, et al. (2008) Co-regulation of yeast purine and phosphate pathways in response to adenylic nucleotide variations. Mol Microbiol 68(6):1583-94 {{SGDpaper|S000126196}} PMID 18433446</ref><ref name='S000061600'>Merkler DJ and Schramm VL (1990) Catalytic and regulatory site composition of yeast AMP deaminase by comparative binding and rate studies. Resolution of the cooperative mechanism. J Biol Chem 265(8):4420-6 {{SGDpaper|S000061600}} PMID 2407736</ref><ref name='S000061601'>Merkler DJ, et al. (1989) AMP deaminase from yeast. Role in AMP degradation, large scale purification, and properties of the native and proteolyzed enzyme. J Biol Chem 264(35):21422-30 {{SGDpaper|S000061601}} PMID 2687280</ref><ref name='S000082032'>Sagot I, et al. (2005) Guanylic nucleotide starvation affects Saccharomyces cerevisiae mother-daughter separation and may be a signal for entry into quiescence. BMC Cell Biol 6(1):24 {{SGDpaper|S000082032}} PMID 15869715</ref><ref name='S000131087'>Saint-Marc C, et al. (2009) Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae. Genetics 183(2):529-38, 1SI-7SI {{SGDpaper|S000131087}} PMID 19635936</ref><ref name='S000132854'>Walther T, et al. (2010) Control of ATP homeostasis during the respiro-fermentative transition in yeast. Mol Syst Biol 6():344 |
− | {{SGDpaper| | + | {{SGDpaper|S000132854}} PMID 20087341</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 13:05, 30 April 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YML035C |
Gene name | AMD1 |
Aliases | AMD3 |
Feature type | ORF, Verified |
Coordinates | Chr XIII:208860..206428 |
Primary SGDID | S000004498 |
Description of YML035C: AMP deaminase; tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; thought to be involved in regulation of intracellular purine (adenine, guanine, and inosine) nucleotide pools[1][2][3][4][5][6]
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References
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- ↑ Gauthier S, et al. (2008) Co-regulation of yeast purine and phosphate pathways in response to adenylic nucleotide variations. Mol Microbiol 68(6):1583-94 SGD PMID 18433446
- ↑ Merkler DJ and Schramm VL (1990) Catalytic and regulatory site composition of yeast AMP deaminase by comparative binding and rate studies. Resolution of the cooperative mechanism. J Biol Chem 265(8):4420-6 SGD PMID 2407736
- ↑ Merkler DJ, et al. (1989) AMP deaminase from yeast. Role in AMP degradation, large scale purification, and properties of the native and proteolyzed enzyme. J Biol Chem 264(35):21422-30 SGD PMID 2687280
- ↑ Sagot I, et al. (2005) Guanylic nucleotide starvation affects Saccharomyces cerevisiae mother-daughter separation and may be a signal for entry into quiescence. BMC Cell Biol 6(1):24 SGD PMID 15869715
- ↑ Saint-Marc C, et al. (2009) Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae. Genetics 183(2):529-38, 1SI-7SI SGD PMID 19635936
- ↑ Walther T, et al. (2010) Control of ATP homeostasis during the respiro-fermentative transition in yeast. Mol Syst Biol 6():344 SGD PMID 20087341
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