Difference between revisions of "YER068W"
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 12:02, 21 February 2007
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| Systematic name | YER068W |
| Gene name | MOT2 |
| Aliases | NOT4, SIG1 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:293048..294811 |
Description of YER068W: Component of the CCR4-NOT complex, which has multiple roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitylates subunits of the nascent polypeptide-associated complex (NAC)[1][2][3][4][5]
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Contents
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References
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- ↑ Panasenko O, et al. (2006) The Yeast Ccr4-Not Complex Controls Ubiquitination of the Nascent-associated Polypeptide (NAC-EGD) Complex. J Biol Chem 281(42):31389-98 SGD PMID 16926149
- ↑ Denis CL, et al. (2001) Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation. Genetics 158(2):627-34 SGD PMID 11404327
- ↑ Badarinarayana V, et al. (2000) Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast. Genetics 155(3):1045-54 SGD PMID 10880468
- ↑ Liu HY, et al. (1998) The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively. EMBO J 17(4):1096-106 SGD PMID 9463387
- ↑ Bai Y, et al. (1999) The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5. Mol Cell Biol 19(10):6642-51 SGD PMID 10490603
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