Difference between revisions of "YHR194W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YHR194W YHR194W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001237 YHR194W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MDM31 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MDM31 ''
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|nowrap| Chr VIII:488657..490396
 
|nowrap| Chr VIII:488657..490396
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001237
 
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'''Description of {{PAGENAME}}:''' Mitochondrial inner membrane protein with similarity to Mdm32p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34<ref name='S000080209'>Dimmer KS, et al. (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15
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'''Description of YHR194W:''' Mitochondrial protein that may have a role in phospholipid metabolism; inner membrane protein with similarity to Mdm32p; required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MMM2, MDM10, MDM12, and MDM34<ref name='S000080209'>Dimmer KS, et al. (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15 {{SGDpaper|S000080209}} PMID 15631992</ref><ref name='S000148784'>Tamura Y, et al. (2012) Role for two conserved intermembrane space proteins, Ups1p and Up2p, in intra-mitochondrial phospholipid trafficking. J Biol Chem ()
  {{SGDpaper|S000080209}} PMID 15631992</ref>
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  {{SGDpaper|S000148784}} PMID 22403410</ref>
 
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==Community Commentary==
 
==Community Commentary==
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 13:05, 23 March 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YHR194W
Gene name MDM31
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:488657..490396
Primary SGDID S000001237


Description of YHR194W: Mitochondrial protein that may have a role in phospholipid metabolism; inner membrane protein with similarity to Mdm32p; required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MMM2, MDM10, MDM12, and MDM34[1][2]




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Community Commentary

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Other

mitochondrial biogenesis

Mdm31p (as well as Mdm32p) seems to play a role in regulation of mitochondrial cation homeostasis and mitochondrial volume. [3] [4]





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References

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  1. Dimmer KS, et al. (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15 SGD PMID 15631992
  2. Tamura Y, et al. (2012) Role for two conserved intermembrane space proteins, Ups1p and Up2p, in intra-mitochondrial phospholipid trafficking. J Biol Chem () SGD PMID 22403410
  3. Kucejova B, et al. (2005) A screen for nigericin-resistant yeast mutants revealed genes controlling mitochondrial volume and mitochondrial cation homeostasis. Genetics 171(2):517-26 SGD PMID 16020778
  4. submitted by Lubomir Tomaska on 2005-12-21

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