Difference between revisions of "YDR195W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YDR195W
Gene name REF2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:848596..850197


Description of YDR195W: RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes[1][2][3]




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References

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  1. Nedea E, et al. (2003) Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends. J Biol Chem 278(35):33000-10 SGD PMID 12819204
  2. Dheur S, et al. (2003) Pti1p and Ref2p found in association with the mRNA 3' end formation complex direct snoRNA maturation. EMBO J 22(11):2831-40 SGD PMID 12773397
  3. Russnak R, et al. (1995) REF2 encodes an RNA-binding protein directly involved in yeast mRNA 3'-end formation. Mol Cell Biol 15(3):1689-97 SGD PMID 7862160

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