Difference between revisions of "YNL036W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004981 YNL036W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NCE103 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NCE103 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XIV: | + | |nowrap| Chr XIV:559814..560479 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004981 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004981 | ||
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| − | '''Description of YNL036W:''' Carbonic anhydrase; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; | + | '''Description of YNL036W:''' Carbonic anhydrase; metalloenzyme that catalyzes CO2 hydration to bicarbonate, which is an important metabolic substrate, and protons; not expressed under conditions of high CO2, such as inside a growing colony, but transcription is induced in response to low CO2 levels, such as on the colony surface in ambient air; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; mutation affects non-classical protein export pathway<ref name='S000077065'>Clark D, et al. (2004) Complementation of the yeast deletion mutant DeltaNCE103 by members of the beta class of carbonic anhydrases is dependent on carbonic anhydrase activity rather than on antioxidant activity. Biochem J 379(Pt 3):609-15 {{SGDpaper|S000077065}} PMID 15096093</ref><ref name='S000053186'>Cleves AE, et al. (1996) A new pathway for protein export in Saccharomyces cerevisiae. J Cell Biol 133(5):1017-26 {{SGDpaper|S000053186}} PMID 8655575</ref><ref name='S000148087'>Cottier F, et al. (2012) The bZIP Transcription Factor Rca1p Is a Central Regulator of a Novel CO(2) Sensing Pathway in Yeast. PLoS Pathog 8(1):e1002485 {{SGDpaper|S000148087}} PMID 22253597</ref><ref name='S000039812'>Gotz R, et al. (1999) Deletion of the carbonic anhydrase-like gene NCE103 of the yeast Saccharomyces cerevisiae causes an oxygen-sensitive growth defect. Yeast 15(10A):855-64 {{SGDpaper|S000039812}} PMID 10407265</ref><ref name='S000136296'>Supuran CT (2010) Carbonic anhydrase inhibition/activation: trip of a scientist around the world in the search of novel chemotypes and drug targets. Curr Pharm Des 16(29):3233-45 |
| − | {{SGDpaper| | + | {{SGDpaper|S000136296}} PMID 20819070</ref> |
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Latest revision as of 13:05, 7 February 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YNL036W |
| Gene name | NCE103 |
| Aliases | NCE3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:559814..560479 |
| Primary SGDID | S000004981 |
Description of YNL036W: Carbonic anhydrase; metalloenzyme that catalyzes CO2 hydration to bicarbonate, which is an important metabolic substrate, and protons; not expressed under conditions of high CO2, such as inside a growing colony, but transcription is induced in response to low CO2 levels, such as on the colony surface in ambient air; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; mutation affects non-classical protein export pathway[1][2][3][4][5]
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References
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- ↑ Clark D, et al. (2004) Complementation of the yeast deletion mutant DeltaNCE103 by members of the beta class of carbonic anhydrases is dependent on carbonic anhydrase activity rather than on antioxidant activity. Biochem J 379(Pt 3):609-15 SGD PMID 15096093
- ↑ Cleves AE, et al. (1996) A new pathway for protein export in Saccharomyces cerevisiae. J Cell Biol 133(5):1017-26 SGD PMID 8655575
- ↑ Cottier F, et al. (2012) The bZIP Transcription Factor Rca1p Is a Central Regulator of a Novel CO(2) Sensing Pathway in Yeast. PLoS Pathog 8(1):e1002485 SGD PMID 22253597
- ↑ Gotz R, et al. (1999) Deletion of the carbonic anhydrase-like gene NCE103 of the yeast Saccharomyces cerevisiae causes an oxygen-sensitive growth defect. Yeast 15(10A):855-64 SGD PMID 10407265
- ↑ Supuran CT (2010) Carbonic anhydrase inhibition/activation: trip of a scientist around the world in the search of novel chemotypes and drug targets. Curr Pharm Des 16(29):3233-45 SGD PMID 20819070
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