Difference between revisions of "YBR186W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 12:02, 21 February 2007

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Systematic name YBR186W
Gene name PCH2
Aliases
Feature type ORF, Verified
Coordinates Chr II:600548..602355


Description of YBR186W: Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in the rDNA[1][2]




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References

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  1. San-Segundo PA and Roeder GS (2000) Role for the silencing protein Dot1 in meiotic checkpoint control. Mol Biol Cell 11(10):3601-15 SGD PMID 11029058
  2. San-Segundo PA and Roeder GS (1999) Pch2 links chromatin silencing to meiotic checkpoint control. Cell 97(3):313-24 SGD PMID 10319812

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