Difference between revisions of "YJR135W-A"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000007348 YJR135W-A] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TIM8 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TIM8 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr X: | + | |nowrap| Chr X:676971..677234 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000007348 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000007348 | ||
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| − | '''Description of YJR135W-A:''' Mitochondrial intermembrane space protein | + | '''Description of YJR135W-A:''' Mitochondrial intermembrane space protein, forms a complex with Tim13p that delivers a subset of hydrophobic proteins to the TIM22 complex for inner membrane insertion; homolog of human TIMM8A, implicated in Mohr-Tranebjaerg syndrome<ref name='S000065406'>Bauer MF and Neupert W (2001) Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration. J Inherit Metab Dis 24(2):166-80 {{SGDpaper|S000065406}} PMID 11405338</ref><ref name='S000131707'>Davis AJ, et al. (2007) The Tim9p/10p and Tim8p/13p complexes bind to specific sites on Tim23p during mitochondrial protein import. Mol Biol Cell 18(2):475-86 {{SGDpaper|S000131707}} PMID 17122363</ref><ref name='S000043156'>Koehler CM, et al. (1999) Human deafness dystonia syndrome is a mitochondrial disease. Proc Natl Acad Sci U S A 96(5):2141-6 {{SGDpaper|S000043156}} PMID 10051608</ref><ref name='S000047441'>Leuenberger D, et al. (1999) Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J 18(17):4816-22 |
| − | {{SGDpaper| | + | {{SGDpaper|S000047441}} PMID 10469659</ref> |
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YJR135W-A |
| Gene name | TIM8 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr X:676971..677234 |
| Primary SGDID | S000007348 |
Description of YJR135W-A: Mitochondrial intermembrane space protein, forms a complex with Tim13p that delivers a subset of hydrophobic proteins to the TIM22 complex for inner membrane insertion; homolog of human TIMM8A, implicated in Mohr-Tranebjaerg syndrome[1][2][3][4]
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References
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- ↑ Bauer MF and Neupert W (2001) Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration. J Inherit Metab Dis 24(2):166-80 SGD PMID 11405338
- ↑ Davis AJ, et al. (2007) The Tim9p/10p and Tim8p/13p complexes bind to specific sites on Tim23p during mitochondrial protein import. Mol Biol Cell 18(2):475-86 SGD PMID 17122363
- ↑ Koehler CM, et al. (1999) Human deafness dystonia syndrome is a mitochondrial disease. Proc Natl Acad Sci U S A 96(5):2141-6 SGD PMID 10051608
- ↑ Leuenberger D, et al. (1999) Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J 18(17):4816-22 SGD PMID 10469659
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