Difference between revisions of "YPR141C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006345 YPR141C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''KAR3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''KAR3 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:817923..815734 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006345 |
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| − | '''Description of | + | '''Description of YPR141C:''' Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate<ref name='S000072838'>Mackey AT and Gilbert SP (2003) The ATPase cross-bridge cycle of the Kar3 motor domain. Implications for single head motility. J Biol Chem 278(6):3527-35 {{SGDpaper|S000072838}} PMID 12446697</ref><ref name='S000043866'>Meluh PB and Rose MD (1990) KAR3, a kinesin-related gene required for yeast nuclear fusion. Cell 60(6):1029-41 {{SGDpaper|S000043866}} PMID 2138512</ref><ref name='S000045728'>Middleton K and Carbon J (1994) KAR3-encoded kinesin is a minus-end-directed motor that functions with centromere binding proteins (CBF3) on an in vitro yeast kinetochore. Proc Natl Acad Sci U S A 91(15):7212-6 {{SGDpaper|S000045728}} PMID 8041770</ref><ref name='S000045191'>Page BD, et al. (1994) Localization of the Kar3 kinesin heavy chain-related protein requires the Cik1 interacting protein. J Cell Biol 124(4):507-19 {{SGDpaper|S000045191}} PMID 8106549</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 |
| − | {{SGDpaper| | + | {{SGDpaper|S000074306}} PMID 14574415</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | === Protein Details === | ||
| + | [[Category:Topic:Protein Details]] | ||
| + | ==== Protein Modification ==== | ||
| + | [[Category:Topic:Protein Details:Protein Modification]] | ||
| + | '''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]] | ||
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| + | Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. <ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref> <ref name = 'CAset7903-2004-01-29'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=7903 Jeff Ubersax] on 2004-01-29</ref> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPR141C |
| Gene name | KAR3 |
| Aliases | OSR11 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:817923..815734 |
| Primary SGDID | S000006345 |
Description of YPR141C: Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate[1][2][3][4][5]
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Community Commentary
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
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References
See Help:References on how to add references
- ↑ Mackey AT and Gilbert SP (2003) The ATPase cross-bridge cycle of the Kar3 motor domain. Implications for single head motility. J Biol Chem 278(6):3527-35 SGD PMID 12446697
- ↑ Meluh PB and Rose MD (1990) KAR3, a kinesin-related gene required for yeast nuclear fusion. Cell 60(6):1029-41 SGD PMID 2138512
- ↑ Middleton K and Carbon J (1994) KAR3-encoded kinesin is a minus-end-directed motor that functions with centromere binding proteins (CBF3) on an in vitro yeast kinetochore. Proc Natl Acad Sci U S A 91(15):7212-6 SGD PMID 8041770
- ↑ Page BD, et al. (1994) Localization of the Kar3 kinesin heavy chain-related protein requires the Cik1 interacting protein. J Cell Biol 124(4):507-19 SGD PMID 8106549
- ↑ 5.0 5.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
SGD PMID 14574415 Cite error: Invalid
<ref>tag; name "S000074306" defined multiple times with different content - ↑ submitted by Jeff Ubersax on 2004-01-29
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
