Difference between revisions of "YPR119W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006323 YPR119W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CLB2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CLB2 '' | ||
Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPR119W |
| Gene name | CLB2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:771653..773128 |
| Primary SGDID | S000006323 |
Description of YPR119W: B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome[1][2][3][4]
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Community Commentary
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DNA and RNA Details
RNA Degradation
mRNA is degraded by RNase MRP [5] [6]
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References
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- ↑ Fitch I, et al. (1992) Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae. Mol Biol Cell 3(7):805-18 SGD PMID 1387566
- ↑ Ghiara JB, et al. (1991) A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell 65(1):163-74 SGD PMID 1849458
- ↑ Mendenhall MD and Hodge AE (1998) Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 62(4):1191-243 SGD PMID 9841670
- ↑ Surana U, et al. (1991) The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae. Cell 65(1):145-61 SGD PMID 1849457
- ↑ Gill T, et al. (2004) RNase MRP cleaves the CLB2 mRNA to promote cell cycle progression: novel method of mRNA degradation. Mol Cell Biol 24(3):945-53 SGD PMID 14729943
- ↑ submitted by Mark Schmitt on 2004-04-07
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