Difference between revisions of "YPL268W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006189 YPL268W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PLC1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PLC1 '' | ||
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− | '''Description of YPL268W:''' | + | '''Description of YPL268W:''' Phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes<ref name='S000040619'>Flick JS and Thorner J (1998) An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae. Genetics 148(1):33-47 {{SGDpaper|S000040619}} PMID 9475719</ref><ref name='S000044075'>Yoko-o T, et al. (1995) Isolation and characterization of temperature-sensitive plc1 mutants of the yeast Saccharomyces cerevisiae. Mol Gen Genet 247(2):148-56 |
− | + | {{SGDpaper|S000044075}} PMID 7753023</ref> | |
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Latest revision as of 07:45, 23 January 2012
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Systematic name | YPL268W |
Gene name | PLC1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XVI:35236..37845 |
Primary SGDID | S000006189 |
Description of YPL268W: Phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes[1][2]
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References
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- ↑ Flick JS and Thorner J (1998) An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae. Genetics 148(1):33-47 SGD PMID 9475719
- ↑ Yoko-o T, et al. (1995) Isolation and characterization of temperature-sensitive plc1 mutants of the yeast Saccharomyces cerevisiae. Mol Gen Genet 247(2):148-56 SGD PMID 7753023
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