Difference between revisions of "YPL164C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006085 YPL164C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MLH3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MLH3 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:241497..239350 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006085 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006085 | ||
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| − | '''Description of YPL164C:''' Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability<ref name='S000042567'>Harfe BD, et al. (2000) Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr Biol 10(3):145-8 {{SGDpaper|S000042567}} PMID 10679328</ref><ref name=' | + | '''Description of YPL164C:''' Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability<ref name='S000047209'>Flores-Rozas H and Kolodner RD (1998) The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. Proc Natl Acad Sci U S A 95(21):12404-9 {{SGDpaper|S000047209}} PMID 9770499</ref><ref name='S000042567'>Harfe BD, et al. (2000) Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr Biol 10(3):145-8 {{SGDpaper|S000042567}} PMID 10679328</ref><ref name='S000064104'>Lipkin SM, et al. (2000) MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability. Nat Genet 24(1):27-35 {{SGDpaper|S000064104}} PMID 10615123</ref><ref name='S000055563'>Wang TF, et al. (1999) Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction. Proc Natl Acad Sci U S A 96(24):13914-9 |
| − | + | {{SGDpaper|S000055563}} PMID 10570173</ref> | |
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPL164C |
| Gene name | MLH3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:241497..239350 |
| Primary SGDID | S000006085 |
Description of YPL164C: Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability[1][2][3][4]
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References
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- ↑ Flores-Rozas H and Kolodner RD (1998) The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. Proc Natl Acad Sci U S A 95(21):12404-9 SGD PMID 9770499
- ↑ Harfe BD, et al. (2000) Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr Biol 10(3):145-8 SGD PMID 10679328
- ↑ Lipkin SM, et al. (2000) MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability. Nat Genet 24(1):27-35 SGD PMID 10615123
- ↑ Wang TF, et al. (1999) Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction. Proc Natl Acad Sci U S A 96(24):13914-9 SGD PMID 10570173
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