Difference between revisions of "YPL153C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006074 YPL153C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RAD53 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RAD53 '' |
Latest revision as of 06:45, 23 January 2012
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Systematic name | YPL153C |
Gene name | RAD53 |
Aliases | LSD1, MEC2, SPK1 |
Feature type | ORF, Verified |
Coordinates | Chr XVI:264192..261727 |
Primary SGDID | S000006074 |
Description of YPL153C: Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication[1][2][3]
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Contents
Community Commentary
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References
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- ↑ Dohrmann PR and Sclafani RA (2006) Novel role for checkpoint Rad53 protein kinase in the initiation of chromosomal DNA replication in Saccharomyces cerevisiae. Genetics 174(1):87-99 SGD PMID 16816422
- ↑ Schwartz MF, et al. (2002) Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint. Mol Cell 9(5):1055-65 SGD PMID 12049741
- ↑ Toh GW and Lowndes NF (2003) Role of the Saccharomyces cerevisiae Rad9 protein in sensing and responding to DNA damage. Biochem Soc Trans 31(Pt 1):242-6 SGD PMID 12546694
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