Difference between revisions of "YPL020C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005941 YPL020C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005941 YPL020C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ULP1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ULP1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XVI:514176..512311
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|nowrap| Chr XVI:514178..512313
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005941
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005941
 
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'''Description of YPL020C:''' Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjugates; specifically required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase<ref name='S000072897'>Li SJ and Hochstrasser M (2003) The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization, and substrate specificity. J Cell Biol 160(7):1069-81 {{SGDpaper|S000072897}} PMID 12654900</ref><ref name='S000068983'>Hochstrasser M (2001) SP-RING for SUMO: new functions bloom for a ubiquitin-like protein. Cell 107(1):5-8 {{SGDpaper|S000068983}} PMID 11595179</ref><ref name='S000059055'>Soustelle C, et al. (2004) A new Saccharomyces cerevisiae strain with a mutant Smt3-deconjugating Ulp1 protein is affected in DNA replication and requires Srs2 and homologous recombination for its viability. Mol Cell Biol 24(12):5130-43
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'''Description of YPL020C:''' Protease that specifically cleaves Smt3p protein conjugates; required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase; sequestered to the nucleolus under stress conditions<ref name='S000068983'>Hochstrasser M (2001) SP-RING for SUMO: new functions bloom for a ubiquitin-like protein. Cell 107(1):5-8 {{SGDpaper|S000068983}} PMID 11595179</ref><ref name='S000072897'>Li SJ and Hochstrasser M (2003) The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization, and substrate specificity. J Cell Biol 160(7):1069-81 {{SGDpaper|S000072897}} PMID 12654900</ref><ref name='S000059055'>Soustelle C, et al. (2004) A new Saccharomyces cerevisiae strain with a mutant Smt3-deconjugating Ulp1 protein is affected in DNA replication and requires Srs2 and homologous recombination for its viability. Mol Cell Biol 24(12):5130-43 {{SGDpaper|S000059055}} PMID 15169880</ref><ref name='S000135053'>Sydorskyy Y, et al. (2010) A Novel Mechanism for SUMO System Control: Regulated Ulp1 Nucleolar Sequestration. Mol Cell Biol 30(18):4452-62
  {{SGDpaper|S000059055}} PMID 15169880</ref>
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  {{SGDpaper|S000135053}} PMID 20647537</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YPL020C
Gene name ULP1
Aliases NIB1
Feature type ORF, Verified
Coordinates Chr XVI:514178..512313
Primary SGDID S000005941


Description of YPL020C: Protease that specifically cleaves Smt3p protein conjugates; required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase; sequestered to the nucleolus under stress conditions[1][2][3][4]




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References

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  1. Hochstrasser M (2001) SP-RING for SUMO: new functions bloom for a ubiquitin-like protein. Cell 107(1):5-8 SGD PMID 11595179
  2. Li SJ and Hochstrasser M (2003) The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization, and substrate specificity. J Cell Biol 160(7):1069-81 SGD PMID 12654900
  3. Soustelle C, et al. (2004) A new Saccharomyces cerevisiae strain with a mutant Smt3-deconjugating Ulp1 protein is affected in DNA replication and requires Srs2 and homologous recombination for its viability. Mol Cell Biol 24(12):5130-43 SGD PMID 15169880
  4. Sydorskyy Y, et al. (2010) A Novel Mechanism for SUMO System Control: Regulated Ulp1 Nucleolar Sequestration. Mol Cell Biol 30(18):4452-62 SGD PMID 20647537

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