Difference between revisions of "YOR281C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005807 YOR281C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005807 YOR281C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PLP2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PLP2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XV:847128..846268
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|nowrap| Chr XV:847129..846269
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005807
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005807
 
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'''Description of YOR281C:''' Essential protein with similarity to phosducins, which are G-protein regulators; interacts with CCT (chaperonin containing TCP-1) complex; lethality of null mutation is complemented by expression of mouse phosducin-like protein MgcPhLP<ref name='S000056422'>Flanary PL, et al. (2000) Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast. J Biol Chem 275(24):18462-9 {{SGDpaper|S000056422}} PMID 10749875</ref><ref name='S000072571'>Lopez P, et al. (2003) A novel germ line-specific gene of the phosducin-like protein (PhLP) family. A meiotic function conserved from yeast to mice. J Biol Chem 278(3):1751-7 {{SGDpaper|S000072571}} PMID 12424248</ref><ref name='S000126550'>Dekker C, et al. (2008) The interaction network of the chaperonin CCT. EMBO J 27(13):1827-39
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'''Description of YOR281C:''' Essential protein that interacts with the CCT (chaperonin containing TCP-1) complex to stimulate actin folding; has similarity to phosducins; null mutant lethality is complemented by mouse phosducin-like protein MgcPhLP<ref name='S000126550'>Dekker C, et al. (2008) The interaction network of the chaperonin CCT. EMBO J 27(13):1827-39 {{SGDpaper|S000126550}} PMID 18511909</ref><ref name='S000056422'>Flanary PL, et al. (2000) Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast. J Biol Chem 275(24):18462-9 {{SGDpaper|S000056422}} PMID 10749875</ref><ref name='S000072571'>Lopez P, et al. (2003) A novel germ line-specific gene of the phosducin-like protein (PhLP) family. A meiotic function conserved from yeast to mice. J Biol Chem 278(3):1751-7 {{SGDpaper|S000072571}} PMID 12424248</ref><ref name='S000130583'>McCormack EA, et al. (2009) Yeast phosducin-like protein 2 acts as a stimulatory co-factor for the folding of actin by the chaperonin CCT via a ternary complex. J Mol Biol 391(1):192-206
  {{SGDpaper|S000126550}} PMID 18511909</ref>
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  {{SGDpaper|S000130583}} PMID 19501098</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YOR281C
Gene name PLP2
Aliases
Feature type ORF, Verified
Coordinates Chr XV:847129..846269
Primary SGDID S000005807


Description of YOR281C: Essential protein that interacts with the CCT (chaperonin containing TCP-1) complex to stimulate actin folding; has similarity to phosducins; null mutant lethality is complemented by mouse phosducin-like protein MgcPhLP[1][2][3][4]




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References

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  1. Dekker C, et al. (2008) The interaction network of the chaperonin CCT. EMBO J 27(13):1827-39 SGD PMID 18511909
  2. Flanary PL, et al. (2000) Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast. J Biol Chem 275(24):18462-9 SGD PMID 10749875
  3. Lopez P, et al. (2003) A novel germ line-specific gene of the phosducin-like protein (PhLP) family. A meiotic function conserved from yeast to mice. J Biol Chem 278(3):1751-7 SGD PMID 12424248
  4. McCormack EA, et al. (2009) Yeast phosducin-like protein 2 acts as a stimulatory co-factor for the folding of actin by the chaperonin CCT via a ternary complex. J Mol Biol 391(1):192-206 SGD PMID 19501098

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