Difference between revisions of "YOR239W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005765 YOR239W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ABP140 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ABP140 '' | ||
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''YOR240W'' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''TRM140, YOR240W'' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XV: | + | |nowrap| Chr XV:784857..786744 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005765 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005765 | ||
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<br> | <br> | ||
| − | '''Description of YOR239W:''' | + | '''Description of YOR239W:''' AdoMet-dependent tRNA methyltransferase and actin binding protein; C-terminal domain is responsible for 3-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA-Thr and tRNA-Ser and contains an S-adenosylmethionine (AdoMet) binding motif; N-terminal actin binding sequence interacts with actin filaments and localizes to actin patches and cables; N- and C-terminal domains are encoded in separate ORFs that are translated into one protein via a +1 frameshift<ref name='S000041861'>Asakura T, et al. (1998) Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae. Oncogene 16(1):121-30 {{SGDpaper|S000041861}} PMID 9467951</ref><ref name='S000145217'>D'Silva S, et al. (2011) A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop. RNA () {{SGDpaper|S000145217}} PMID 21518804</ref><ref name='S000145216'>Noma A, et al. (2011) Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae. RNA () |
| − | {{SGDpaper| | + | {{SGDpaper|S000145216}} PMID 21518805</ref> |
<br> | <br> | ||
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YOR239W |
| Gene name | ABP140 |
| Aliases | TRM140, YOR240W |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:784857..786744 |
| Primary SGDID | S000005765 |
Description of YOR239W: AdoMet-dependent tRNA methyltransferase and actin binding protein; C-terminal domain is responsible for 3-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA-Thr and tRNA-Ser and contains an S-adenosylmethionine (AdoMet) binding motif; N-terminal actin binding sequence interacts with actin filaments and localizes to actin patches and cables; N- and C-terminal domains are encoded in separate ORFs that are translated into one protein via a +1 frameshift[1][2][3]
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References
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- ↑ Asakura T, et al. (1998) Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae. Oncogene 16(1):121-30 SGD PMID 9467951
- ↑ D'Silva S, et al. (2011) A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop. RNA () SGD PMID 21518804
- ↑ Noma A, et al. (2011) Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae. RNA () SGD PMID 21518805
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