Difference between revisions of "YOR232W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005758 YOR232W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005758 YOR232W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MGE1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MGE1 ''

Latest revision as of 06:45, 23 January 2012

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Systematic name YOR232W
Gene name MGE1
Aliases GRPE, YGE1
Feature type ORF, Verified
Coordinates Chr XV:774573..775259
Primary SGDID S000005758


Description of YOR232W: Mitochondrial matrix cochaperone, acts as a nucleotide release factor for Ssc1p in protein translocation and folding; also acts as cochaperone for Ssq1p in folding of Fe-S cluster proteins; homolog of E. coli GrpE[1][2][3][4][5][6]




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References

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  1. Bolliger L, et al. (1994) A mitochondrial homolog of bacterial GrpE interacts with mitochondrial hsp70 and is essential for viability. EMBO J 13(8):1998-2006 SGD PMID 8168496
  2. Deloche O and Georgopoulos C (1996) Purification and biochemical properties of Saccharomyces cerevisiae's Mge1p, the mitochondrial cochaperone of Ssc1p. J Biol Chem 271(39):23960-6 SGD PMID 8798629
  3. Ikeda E, et al. (1994) YGE1 is a yeast homologue of Escherichia coli grpE and is required for maintenance of mitochondrial functions. FEBS Lett 339(3):265-8 SGD PMID 8112465
  4. Laloraya S, et al. (1994) A role for a eukaryotic GrpE-related protein, Mge1p, in protein translocation. Proc Natl Acad Sci U S A 91(14):6481-5 SGD PMID 8022808
  5. Miao B, et al. (1997) Mge1 functions as a nucleotide release factor for Ssc1, a mitochondrial Hsp70 of Saccharomyces cerevisiae. J Mol Biol 265(5):541-52 SGD PMID 9048947
  6. Schmidt S, et al. (2001) The two mitochondrial heat shock proteins 70, Ssc1 and Ssq1, compete for the cochaperone Mge1. J Mol Biol 313(1):13-26 SGD PMID 11601843

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