Difference between revisions of "YOR156C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005682 YOR156C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005682 YOR156C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NFI1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NFI1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XV:630541..628361
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|nowrap| Chr XV:630540..628360
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005682
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005682
 
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'''Description of YOR156C:''' SUMO ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins; involved in maintenance of proper telomere length<ref name='S000114270'>Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 {{SGDpaper|S000114270}} PMID 15161972</ref><ref name='S000068983'>Hochstrasser M (2001) SP-RING for SUMO: new functions bloom for a ubiquitin-like protein. Cell 107(1):5-8 {{SGDpaper|S000068983}} PMID 11595179</ref><ref name='S000066051'>Johnson ES and Gupta AA (2001) An E3-like factor that promotes SUMO conjugation to the yeast septins. Cell 106(6):735-44
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'''Description of YOR156C:''' SUMO E3 ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins; primary E3 ligase for Sir4p; sumoylates Yku70p/Yku80p and Sir4p in vivo to promote chromatin anchoring; promotes telomere anchoring to the nuclear envelope; involved in maintenance of proper telomere length<ref name='S000114270'>Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 {{SGDpaper|S000114270}} PMID 15161972</ref><ref name='S000145714'>Ferreira HC, et al. (2011) The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast.LID - 10.1038/ncb2263 [doi] Nat Cell Biol () {{SGDpaper|S000145714}} PMID 21666682</ref><ref name='S000068983'>Hochstrasser M (2001) SP-RING for SUMO: new functions bloom for a ubiquitin-like protein. Cell 107(1):5-8 {{SGDpaper|S000068983}} PMID 11595179</ref><ref name='S000066051'>Johnson ES and Gupta AA (2001) An E3-like factor that promotes SUMO conjugation to the yeast septins. Cell 106(6):735-44
 
  {{SGDpaper|S000066051}} PMID 11572779</ref>
 
  {{SGDpaper|S000066051}} PMID 11572779</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YOR156C
Gene name NFI1
Aliases SIZ2
Feature type ORF, Verified
Coordinates Chr XV:630540..628360
Primary SGDID S000005682


Description of YOR156C: SUMO E3 ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins; primary E3 ligase for Sir4p; sumoylates Yku70p/Yku80p and Sir4p in vivo to promote chromatin anchoring; promotes telomere anchoring to the nuclear envelope; involved in maintenance of proper telomere length[1][2][3][4]




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References

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  1. Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
  2. Ferreira HC, et al. (2011) The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast.LID - 10.1038/ncb2263 [doi] Nat Cell Biol () SGD PMID 21666682
  3. Hochstrasser M (2001) SP-RING for SUMO: new functions bloom for a ubiquitin-like protein. Cell 107(1):5-8 SGD PMID 11595179
  4. Johnson ES and Gupta AA (2001) An E3-like factor that promotes SUMO conjugation to the yeast septins. Cell 106(6):735-44 SGD PMID 11572779

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