Difference between revisions of "YOR018W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005544 YOR018W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ROD1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ROD1 '' | ||
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' '' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''ART4'' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
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| − | '''Description of YOR018W:''' Membrane protein; overexpression confers resistance to the GST substrate o-dinitrobenzene | + | '''Description of YOR018W:''' Membrane protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; overexpression confers resistance to the GST substrate o-dinitrobenzene,zinc, and calcium; proposed to regulate the endocytosis of plasma membrane proteins<ref name='S000070307'>Andoh T, et al. (2002) PY motifs of Rod1 are required for binding to Rsp5 and for drug resistance. FEBS Lett 525(1-3):131-4 {{SGDpaper|S000070307}} PMID 12163175</ref><ref name='S000128206'>Lin CH, et al. (2008) Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135(4):714-25 {{SGDpaper|S000128206}} PMID 18976803</ref><ref name='S000054414'>Wu AL, et al. (1996) ROD1, a novel gene conferring multiple resistance phenotypes in Saccharomyces cerevisiae. J Biol Chem 271(6):2914-20 |
{{SGDpaper|S000054414}} PMID 8621680</ref> | {{SGDpaper|S000054414}} PMID 8621680</ref> | ||
<br> | <br> | ||
Latest revision as of 06:45, 23 January 2012
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| Systematic name | YOR018W |
| Gene name | ROD1 |
| Aliases | ART4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:364369..366882 |
| Primary SGDID | S000005544 |
Description of YOR018W: Membrane protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; overexpression confers resistance to the GST substrate o-dinitrobenzene,zinc, and calcium; proposed to regulate the endocytosis of plasma membrane proteins[1][2][3]
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References
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- ↑ Andoh T, et al. (2002) PY motifs of Rod1 are required for binding to Rsp5 and for drug resistance. FEBS Lett 525(1-3):131-4 SGD PMID 12163175
- ↑ Lin CH, et al. (2008) Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135(4):714-25 SGD PMID 18976803
- ↑ Wu AL, et al. (1996) ROD1, a novel gene conferring multiple resistance phenotypes in Saccharomyces cerevisiae. J Biol Chem 271(6):2914-20 SGD PMID 8621680
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