Difference between revisions of "YOR018W"

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{|{{Prettytable}} align = 'right' width = '200px'
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YOR018W YOR018W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005544 YOR018W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ROD1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ROD1 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''ART4''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr XV:364369..366882
 
|nowrap| Chr XV:364369..366882
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005544
 
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'''Description of {{PAGENAME}}:''' Membrane protein; overexpression confers resistance to the GST substrate o-dinitrobenzene as well as to zinc and calcium; contains 2 PY motifs, which are required for Rod1p interaction with Rsp5p, a hect-type ubiquitin ligase<ref name='S000070307'>Andoh T, et al. (2002) PY motifs of Rod1 are required for binding to Rsp5 and for drug resistance. FEBS Lett 525(1-3):131-4 {{SGDpaper|S000070307}} PMID 12163175</ref><ref name='S000054414'>Wu AL, et al. (1996) ROD1, a novel gene conferring multiple resistance phenotypes in Saccharomyces cerevisiae. J Biol Chem 271(6):2914-20
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'''Description of YOR018W:''' Membrane protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; overexpression confers resistance to the GST substrate o-dinitrobenzene,zinc, and calcium; proposed to regulate the endocytosis of plasma membrane proteins<ref name='S000070307'>Andoh T, et al. (2002) PY motifs of Rod1 are required for binding to Rsp5 and for drug resistance. FEBS Lett 525(1-3):131-4 {{SGDpaper|S000070307}} PMID 12163175</ref><ref name='S000128206'>Lin CH, et al. (2008) Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135(4):714-25 {{SGDpaper|S000128206}} PMID 18976803</ref><ref name='S000054414'>Wu AL, et al. (1996) ROD1, a novel gene conferring multiple resistance phenotypes in Saccharomyces cerevisiae. J Biol Chem 271(6):2914-20
 
  {{SGDpaper|S000054414}} PMID 8621680</ref>
 
  {{SGDpaper|S000054414}} PMID 8621680</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YOR018W
Gene name ROD1
Aliases ART4
Feature type ORF, Verified
Coordinates Chr XV:364369..366882
Primary SGDID S000005544


Description of YOR018W: Membrane protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; overexpression confers resistance to the GST substrate o-dinitrobenzene,zinc, and calcium; proposed to regulate the endocytosis of plasma membrane proteins[1][2][3]




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References

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  1. Andoh T, et al. (2002) PY motifs of Rod1 are required for binding to Rsp5 and for drug resistance. FEBS Lett 525(1-3):131-4 SGD PMID 12163175
  2. Lin CH, et al. (2008) Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135(4):714-25 SGD PMID 18976803
  3. Wu AL, et al. (1996) ROD1, a novel gene conferring multiple resistance phenotypes in Saccharomyces cerevisiae. J Biol Chem 271(6):2914-20 SGD PMID 8621680

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