Difference between revisions of "YOL115W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005475 YOL115W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PAP2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PAP2 '' | ||
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| − | '''Description of YOL115W:''' | + | '''Description of YOL115W:''' Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Trf5p<ref name='S000124622'>Gellon L, et al. (2008) Intrinsic 5'-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repair. DNA Repair (Amst) 7(2):187-98 {{SGDpaper|S000124622}} PMID 17983848</ref><ref name='S000081843'>LaCava J, et al. (2005) RNA degradation by the exosome is promoted by a nuclear polyadenylation complex. Cell 121(5):713-24 {{SGDpaper|S000081843}} PMID 15935758</ref><ref name='S000081438'>Vanacova S, et al. (2005) A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS Biol 3(6):e189 {{SGDpaper|S000081438}} PMID 15828860</ref><ref name='S000081864'>Wyers F, et al. (2005) Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase. Cell 121(5):725-37 |
| − | {{SGDpaper| | + | {{SGDpaper|S000081864}} PMID 15935759</ref> |
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YOL115W |
| Gene name | PAP2 |
| Aliases | TRF4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:101475..103229 |
| Primary SGDID | S000005475 |
Description of YOL115W: Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Trf5p[1][2][3][4]
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References
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- ↑ Gellon L, et al. (2008) Intrinsic 5'-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repair. DNA Repair (Amst) 7(2):187-98 SGD PMID 17983848
- ↑ LaCava J, et al. (2005) RNA degradation by the exosome is promoted by a nuclear polyadenylation complex. Cell 121(5):713-24 SGD PMID 15935758
- ↑ Vanacova S, et al. (2005) A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS Biol 3(6):e189 SGD PMID 15828860
- ↑ Wyers F, et al. (2005) Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase. Cell 121(5):725-37 SGD PMID 15935759
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