Difference between revisions of "YNR057C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YNR057C YNR057C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005340 YNR057C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''BIO4 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''BIO4 ''
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|nowrap| Chr XIV:734069..733356
 
|nowrap| Chr XIV:734069..733356
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005340
 
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'''Description of {{PAGENAME}}:''' Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels<ref name='S000075799'>Shakoury-Elizeh M, et al. (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15(3):1233-43 {{SGDpaper|S000075799}} PMID 14668481</ref><ref name='S000055833'>Phalip V, et al. (1999) Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake. Gene 232(1):43-51
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'''Description of YNR057C:''' Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels<ref name='S000055833'>Phalip V, et al. (1999) Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake. Gene 232(1):43-51 {{SGDpaper|S000055833}} PMID 10333520</ref><ref name='S000075799'>Shakoury-Elizeh M, et al. (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15(3):1233-43
  {{SGDpaper|S000055833}} PMID 10333520</ref>
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  {{SGDpaper|S000075799}} PMID 14668481</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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=== Other ===
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[[Category:Topic:Other]]
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==== Gene Origin ====
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Horizontally transferred from alpha proteobacteria <ref name='S000082122'>Hall C, et al. (2005) Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. Eukaryot Cell 4(6):1102-15 {{SGDpaper|S000082122}} PMID 15947202</ref> <ref name = 'CAset10543-2006-06-09'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=10543 Charles Hall] on 2006-06-09</ref>
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YNR057C
Gene name BIO4
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:734069..733356
Primary SGDID S000005340


Description of YNR057C: Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels[1][2]




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Community Commentary

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Other

Gene Origin

Horizontally transferred from alpha proteobacteria [3] [4]





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References

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  1. Phalip V, et al. (1999) Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake. Gene 232(1):43-51 SGD PMID 10333520
  2. Shakoury-Elizeh M, et al. (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15(3):1233-43 SGD PMID 14668481
  3. Hall C, et al. (2005) Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. Eukaryot Cell 4(6):1102-15 SGD PMID 15947202
  4. submitted by Charles Hall on 2006-06-09

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