Difference between revisions of "YNL305C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005249 YNL305C] |
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||'' '' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''BXI1 '' |
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' '' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''YBH3'' |
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XIV:59791..58898 | |nowrap| Chr XIV:59791..58898 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005249 |
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| − | '''Description of | + | '''Description of YNL305C:''' Protein involved in apoptosis; variously described as containing a BCL-2 homology (BH3) domain or as a member of the BAX inhibitor family; reported to promote apoptosis under some conditions and to inhibit it in others; localizes to ER and vacuole; may link the unfolded protein response to apoptosis via regulation of calcium-mediated signaling; translocates to mitochondria under apoptosis-inducing conditions in a process involving Mir1p and Cor1p<ref name='S000145692'>Buttner S, et al. (2011) A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis.LID - 10.1038/emboj.2011.197 [doi] EMBO J () {{SGDpaper|S000145692}} PMID 21673659</ref><ref name='S000145684'>Cebulski J, et al. (2011) Yeast Bax Inhibitor, Bxi1p, Is an ER-Localized Protein That Links the Unfolded Protein Response and Programmed Cell Death in Saccharomyces cerevisiae. PLoS One 6(6):e20882 {{SGDpaper|S000145684}} PMID 21673967</ref><ref name='S000139840'>Chae HJ, et al. (2003) Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast. Gene 323():101-13 {{SGDpaper|S000139840}} PMID 14659883</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 {{SGDpaper|S000071347}} PMID 12140549</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 |
| − | {{SGDpaper| | + | {{SGDpaper|S000074185}} PMID 14562095</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YNL305C |
| Gene name | BXI1 |
| Aliases | YBH3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:59791..58898 |
| Primary SGDID | S000005249 |
Description of YNL305C: Protein involved in apoptosis; variously described as containing a BCL-2 homology (BH3) domain or as a member of the BAX inhibitor family; reported to promote apoptosis under some conditions and to inhibit it in others; localizes to ER and vacuole; may link the unfolded protein response to apoptosis via regulation of calcium-mediated signaling; translocates to mitochondria under apoptosis-inducing conditions in a process involving Mir1p and Cor1p[1][2][3][4][5]
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Contents
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References
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- Jump up ↑ Buttner S, et al. (2011) A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis.LID - 10.1038/emboj.2011.197 [doi] EMBO J () SGD PMID 21673659
- Jump up ↑ Cebulski J, et al. (2011) Yeast Bax Inhibitor, Bxi1p, Is an ER-Localized Protein That Links the Unfolded Protein Response and Programmed Cell Death in Saccharomyces cerevisiae. PLoS One 6(6):e20882 SGD PMID 21673967
- Jump up ↑ Chae HJ, et al. (2003) Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast. Gene 323():101-13 SGD PMID 14659883
- Jump up ↑ Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
- Jump up ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
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