Difference between revisions of "YNL272C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005216 YNL272C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SEC2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SEC2 '' | ||
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| − | '''Description of YNL272C:''' Guanyl-nucleotide exchange factor for the small G-protein Sec4p | + | '''Description of YNL272C:''' Guanyl-nucleotide exchange factor for the small G-protein Sec4p; essential for post-Golgi vesicle transport and for autophagy; associates with the exocyst, via exocyst subunit Sec15p, on secretory vesicles<ref name='S000133980'>Geng J, et al. (2010) Post-golgi sec proteins are required for autophagy in Saccharomyces cerevisiae. Mol Biol Cell 21(13):2257-69 {{SGDpaper|S000133980}} PMID 20444978</ref><ref name='S000122541'>Medkova M, et al. (2006) The rab exchange factor Sec2p reversibly associates with the exocyst. Mol Biol Cell 17(6):2757-69 {{SGDpaper|S000122541}} PMID 16611746</ref><ref name='S000051492'>Walch-Solimena C, et al. (1997) Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles. J Cell Biol 137(7):1495-509 |
{{SGDpaper|S000051492}} PMID 9199166</ref> | {{SGDpaper|S000051492}} PMID 9199166</ref> | ||
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YNL272C |
| Gene name | SEC2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:129084..126805 |
| Primary SGDID | S000005216 |
Description of YNL272C: Guanyl-nucleotide exchange factor for the small G-protein Sec4p; essential for post-Golgi vesicle transport and for autophagy; associates with the exocyst, via exocyst subunit Sec15p, on secretory vesicles[1][2][3]
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References
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- ↑ Geng J, et al. (2010) Post-golgi sec proteins are required for autophagy in Saccharomyces cerevisiae. Mol Biol Cell 21(13):2257-69 SGD PMID 20444978
- ↑ Medkova M, et al. (2006) The rab exchange factor Sec2p reversibly associates with the exocyst. Mol Biol Cell 17(6):2757-69 SGD PMID 16611746
- ↑ Walch-Solimena C, et al. (1997) Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles. J Cell Biol 137(7):1495-509 SGD PMID 9199166
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