Difference between revisions of "YNL100W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005044 YNL100W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005044 YNL100W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''AIM37 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''AIM37 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''MCS27''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
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'''Description of YNL100W:''' Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; null mutant is viable and displays reduced respiratory growth and reduced frequency of mitochondrial genome loss<ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 {{SGDpaper|S000071347}} PMID 12140549</ref><ref name='S000129658'>Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 {{SGDpaper|S000129658}} PMID 19300474</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
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'''Description of YNL100W:''' Mitochondrial inner membrane protein; component of the mitochondrial inner membrane organizing system (MitOS, MICOS, or MINOS), a scaffold-like structure on the intermembrane space side of the inner membrane which has a role in the maintenance of crista junctions and inner membrane architecture<ref name='S000147113'>Harner M, et al. (2011) The mitochondrial contact site complex, a determinant of mitochondrial architecture.LID - 10.1038/emboj.2011.379 [doi] EMBO J () {{SGDpaper|S000147113}} PMID 22009199</ref><ref name='S000147046'>Hoppins S, et al. (2011) A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J Cell Biol () {{SGDpaper|S000147046}} PMID 21987634</ref><ref name='S000146902'>von der Malsburg K, et al. (2011) Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis. Dev Cell ()
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  {{SGDpaper|S000117178}} PMID 16823961</ref>
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  {{SGDpaper|S000146902}} PMID 21944719</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YNL100W
Gene name AIM37
Aliases MCS27
Feature type ORF, Verified
Coordinates Chr XIV:437613..438317
Primary SGDID S000005044


Description of YNL100W: Mitochondrial inner membrane protein; component of the mitochondrial inner membrane organizing system (MitOS, MICOS, or MINOS), a scaffold-like structure on the intermembrane space side of the inner membrane which has a role in the maintenance of crista junctions and inner membrane architecture[1][2][3]




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References

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  1. ↑ Harner M, et al. (2011) The mitochondrial contact site complex, a determinant of mitochondrial architecture.LID - 10.1038/emboj.2011.379 [doi] EMBO J () SGD PMID 22009199
  2. ↑ Hoppins S, et al. (2011) A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J Cell Biol () SGD PMID 21987634
  3. ↑ von der Malsburg K, et al. (2011) Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis. Dev Cell () SGD PMID 21944719

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