Difference between revisions of "YMR260C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004873 YMR260C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004873 YMR260C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TIF11 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TIF11 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIII:789838..789377
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|nowrap| Chr XIII:789839..789378
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004873
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004873
 
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'''Description of YMR260C:''' Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3<ref name='S000045276'>Wei CL, et al. (1995) Characterization of yeast translation initiation factor 1A and cloning of its essential gene. J Biol Chem 270(39):22788-94 {{SGDpaper|S000045276}} PMID 7559407</ref><ref name='S000081107'>Maag D, et al. (2005) A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon. Mol Cell 17(2):265-75 {{SGDpaper|S000081107}} PMID 15664195</ref><ref name='S000072611'>Olsen DS, et al. (2003) Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo. EMBO J 22(2):193-204
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'''Description of YMR260C:''' Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3<ref name='S000081107'>Maag D, et al. (2005) A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon. Mol Cell 17(2):265-75 {{SGDpaper|S000081107}} PMID 15664195</ref><ref name='S000072611'>Olsen DS, et al. (2003) Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo. EMBO J 22(2):193-204 {{SGDpaper|S000072611}} PMID 12514125</ref><ref name='S000045276'>Wei CL, et al. (1995) Characterization of yeast translation initiation factor 1A and cloning of its essential gene. J Biol Chem 270(39):22788-94
  {{SGDpaper|S000072611}} PMID 12514125</ref>
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  {{SGDpaper|S000045276}} PMID 7559407</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YMR260C
Gene name TIF11
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:789839..789378
Primary SGDID S000004873


Description of YMR260C: Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3[1][2][3]




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References

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  1. Maag D, et al. (2005) A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon. Mol Cell 17(2):265-75 SGD PMID 15664195
  2. Olsen DS, et al. (2003) Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo. EMBO J 22(2):193-204 SGD PMID 12514125
  3. Wei CL, et al. (1995) Characterization of yeast translation initiation factor 1A and cloning of its essential gene. J Biol Chem 270(39):22788-94 SGD PMID 7559407

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